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Table 2 Performance of the classification trees

From: The pediatric sepsis biomarker risk model

 

Derivation cohort

Test cohort

Updated model

Number of subjects

220

135

355

Number of true positives

21

16

38

Number of true negatives

169

75

233

Number of false positives

28

42

81

Number of false negatives

2

2

3

Sensitivity

91% (70, 98)

89% (64, 98)

93% (79, 98)

Specificity

86% (80, 90)

64% (55, 73)

74% (69, 79)

Positive predictive value

43% (29, 58)

28% (17, 41)

32% (24, 41)

Negative predictive value

99% (95, 100)

97% (90, 100)

99% (96, 100)

+Likelihood ratio

6.4 (4.5, 9.3)

2.5 (1.8, 3.3)

3.6 (2.9, 4.4)

-Likelihood ratio

0.1 (0.0, 0.4)

0.2 (0.0, 0.6)

0.1 (0.0, 0.3)

Area under the curve

0.885

0.759

0.883