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Table 3 Sensitivity analysis of outcomes according to the different effect models

From: Can dexmedetomidine be a safe and efficacious sedative agent in post-cardiac surgery patients? a meta-analysis

Outcomes

Fixed-effect model

Random-effect model

Length of mechanical ventilation

MD

-1.39 (-2.04, -0.74)

-2.70 (-5.05, -0.35)

Duration in ICU

MD

-0.22 (-1.85, 1.41)

-3.44 (-11.40, 4.52)

Hospital stay

MD

-0.28 (-0.64, 0.07)

-0.36 (-0.83, 0.11)

Morphine equivalents

MD

1.11 (0.11, 2.11)

0.45 (-1.86, 2.77)

Hypotension

RR

0.94 (0.80, 1.10)

0.99 (0.72, 1.36)

Bradycardia

RR

2.08 (1.16, 3.74)

2.04 (1.12, 3.68)

Delirium

RR

0.36 (0.21, 0.64)

0.39 (0.13, 1.19)

Ventricular tachycardia

RR

0.27 (0.08, 0.97)

0.36 (0.07, 1.96)

Atrial fibrillation

RR

0.90 (0.62, 1.29)

0.88 (0.62, 1.27)

Hyperglycemia

RR

0.78 (0.61, 0.99)

0.78 (0.62, 0.99)

Vomiting and nausea

RR

1.02 (0.72, 1.46)

1.02 (0.71, 1.46)

Reintubation within 48 hours

RR

1.62 (0.51, 5.13)

1.51 (0.46, 4.96)

Any postoperative infection

RR

0.89 (0.38, 2.12)

0.89 (0.30, 2.64)

Hospital mortality

RR

0.79 (0.57, 1.09)

0.72 (0.37, 1.39)

  1. MD: mean difference; RR: risk ratio. Values in parentheses are 95% CI.