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Table 1 Composition and buffer strength of the different citrate solutions

From: Bench-to-bedside review: Citrate for continuous renal replacement therapy, from science to practice

 

Separate citrate solutions

Citrate-buffered pre-dilution replacement fluid

 

TSC

TSC + Ca

ACD-A

TSC + Ca + NaCl

TSC + NaCl

Citrate in balanced fluid

Na+, mmol/L

210-3,000

1,352

224

136

140

140-159

H+, mmol/L (% of cations)

None

148

115 (33)

6

None

None

Citrate3-, mmol/L

68-1,000

450 (+50)a

113

10 (+2)b

18 or 23

13.3-20

Glucose, mmol/L

None

None

139

None

None

±5

K+, mmol/L

None

None

None

None

None

0-3

Mg2+, mmol/L

None

None

None

None

None

0-0.75

Cl2-, mmol/L

None

None

None

106

86 or 81

99-108

SIDec, mmol/L

3,000

1,352

224

30

54

33-54

SIDe per mmol citrate

3

2.7

2.0

3

3

2.25-3

  1. aThe 50 citrate ions are from citric acid. bThe two citrate ions are from citric acid. cSIDe: effective strong ion difference as calculated after metabolism of citrate: (Na++K++Ca2++Mg2+) - (Cl-). ACD-A, acid citrate dextrose; Ca, citric acid; NaCl, saline; SIDe, effective strong ion difference; TSC, trisodium citrate.