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Figure 1 | Critical Care

Figure 1

From: Therapeutic efficacy of CXCR3 blockade in an experimental model of severe sepsis

Figure 1

Treatment with anti-CXCR IgG improves survival during cecal ligation and puncture-induced sepsis. Mice were treated with anti-CXC chemokine receptor 3 (anti-CXCR3) IgG (100 μg) or nonspecific IgG (100 μg) 24 hours prior to (n = 10 mice per group), 2 hours after (n = 20 mice per group) or 6 hours after (n = 20 mice per group) cecal ligation and puncture (CLP). Mice were followed for survival over a 2-week period. *P <0.05 compared with nonspecific IgG.

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