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Table 3 Characteristics of patients according to mean arterial pressure

From: Doppler resistive index to reflect regulation of renal vascular tone during sepsis and acute kidney injury

  <70 mm Hg 70 to 85 mm Hg >85 mm Hg P value
No acute kidney injury (n = 13) (n = 19) (n = 10)  
   Mean arterial pressure, mm Hg 63 (59-66)a,b 79 (74-81)b,c 93 (89-100)a,c <0.001
   Heart rate, beats per minute 88 (77-92)a 98 (90-115)b,c 90 (64-96)a 0.026
   Fluid balance on inclusion day, mL 1,400 (865-2,735) 1,680 (990-2,560) 1,237 (699-2,376) 0.7
   Norepinephrine infusion, number (percentage) 6 (46) 9 (47) 3 (30) 0.6
   Norepinephrine dose, μg/kg per minute 0.20 (0.06-0.38) 0.19 (0.05-0.36) 0.17 (0.06-0.47) 0.9
   Cardiac index, L/minute per m² 2.6 (1.7-3.0) 4.1 (3.1-7.8) 2.7 (1.9-5.0) 0.1
   PaO2/FiO2 ratio 280 (116-310) 240 (107-302) 229 (193-395) 0.4
   Resistance index 0.74 (0.70-0.78) 0.72 (0.68-0.77) 0.69 (0.67-0.72)c 0.04
Acute kidney injury (n = 25) (n = 14) (n = 13)  
   Mean arterial pressure, mm Hg 65 (62-66)a,b 73 (70-76)b,c 94 (89-104)a,c <0.001
   Heart rate, beats per minute 95 (83-124) 90 (82-117) 89 (79-112) 0.7
   Fluid balance on inclusion day, mL 2,605 (1,303-3,767) 2,650 (2,184-3,481) 1,480 (1,105-2,400) 0.1
   Norepinephrine infusion, number (percentage) 16 (64) 10 (71) 3 (23) 0.02
   Norepinephrine dose, μg/kg per minute 0.20 (0.06-0.38) 0.19 (0.05-0.36) 0.17 (0.06-0.47) 0.9
   Cardiac index, L/minute per m² 2.8 (2.4-3.6) 3.0 (1.8-5.2) 3.7 (3.1-5.9) 0.4
   PaO2/FiO2 ratio 140 (110-270) 252 (180-310) 180 (134-270) 0.06
   Resistance index 0.76 (0.73.80) 0.74 (0.66-0.78) 0.78 (0.73-0.82) 0.1
  1. Results are expressed as median (interquartile range). P value refers to between-group comparisons (Kruskal-Wallis one-way analysis of variance with post hoc analysis). aP <0.05 compared with mean arterial pressure (MAP) 70-85 mm Hg group. bP <0.05 compared with MAP >85 mm Hg group. cP <0.05 compared with MAP <70 mm Hg group. PaO2/FiO2, arterial partial pressure of oxygen/fraction of inspired oxygen.