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Table 2 Continuing challenges relative to ventilator management

From: Mechanical ventilation: past lessons and the near future

Address and minimize heterogeneity of mechanics

Minimize demands for ventilation

Optimize sedation and comfort

Minimize time on ventilator

Coordinate appropriately with ventilatory drive

Automate adjustment for changing patient needs

Safely help the patient adapt to the disease

Prevent infection and adult respiratory distress syndrome