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Figure 6 | Critical Care

Figure 6

From: Bench-to-bedside review: Clinical experience with the endotoxin activity assay

Figure 6

Endotoxin activity assay scattergram values for patients (n = 42) undergoing polymyxin B column hemoperfusion. Mean endotoxin activity assay (EAA) values are indicated in bold. Samples were drawn before perfusion (baseline, n = 42) and at 4 (n = 42) and 12 hours post-column treatment (n = 42). At 4 hours the mean EAA was 0.57 (*P < 0.05 versus baseline) and 0.45 at 12 hours (**P < 0.01 versus baseline). All patients showed a decline in EAA values at 12 hours post-column treatment. There was no placebo control group in this study. The red circles highlight the significant drop in mean EAA values from pre-treatment to 12 hours post-treatment with an estimated 50-100 fold reduction in endotoxin concentration.

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