Figure 5From: Bench-to-bedside review: Clinical experience with the endotoxin activity assayInhibition study with polymyxin B. Fifteen consecutive ICU patients with elevated endotoxin levels had endotoxin acitivity assays repeated following addition of polymyxin B to their blood (300 μg/ml for 20 minutes at 37°C). The dose response for the second International WHO standard E. coli 0113:H10:K lipopolysaccharide (LPS) was used to estimate the endotoxin concentration in the patient blood samples.Back to article page