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Table 3 Effects of mannitol on systemic hemodynamic variables

From: Mannitol increases renal blood flow and maintains filtration fraction and oxygenation in postoperative acute kidney injury: a prospective interventional study

 

C1

C2

M1

M2

P value

MAP (mm Hg)

76.0 ± 1.30

75.4 ± 1.43

75.3 ± 0.91

74.6 ± 1.29

0.467

CI (L/min/m2)

2.9 ± 0.20

2.9 ± 0.21

3.0 ± 0.21

3.0 ± 0.21

0.109

SVI (ml/beat/m2)

30.5 ± 2.57

31.1 ± 2.63

31.8 ± 2.68

32.2 ± 2.55

0.046

HR (beats/min)

99.5 ± 5.78

97.1 ± 4.87

96.7 ± 4.99

96.0 ± 4.77

0.190

SVRI (dynes s/cm5/m2)

1,794 ± 112

1,776 ± 138

1,738 ± 124

1,708 ± 132

0.074

PVRI (dynes s/cm5/m2)

272 ± 26.6

278 ± 26.0

269 ± 22.9

260 ± 17.0

0.573

CVP (mm Hg)

12.6 ± 1.02

13.2 ± 0.90

13.2 ± 1.07

13.0 ± 1.04

0.531

MPAP (mm Hg)

27.1 ± 2.21

27.2 ± 2.00

27.3 ± 2.16

26.9 ± 2.06

0.933

PCWP (mm Hg)

17.3 ± 2.00

17.3 ± 1.95

17.5 ± 2.09

17.4 ± 2.02

0.720

Hct

0.313 ± 0.015

0.316 ± 0.012

0.309 ± 0.012

0.309 ± 0.013

0.012

Body temperature (oC)

37.55 ± 0.23

37.58 ± 0.21

37.54 ± 0.20

37.50 ± 0.19

0.182

  1. Data are presented as mean ± SEM. C1, first control period before mannitol infusion; C2, second control period before mannitol infusion; CI, cardiac index; CVP, central venous pressure; Hct, hematocrit; HR, heart rate; M1, first period with mannitol infusion (150 mg/ml, infusion rate of 0.5 ml/kg/h); M2, second period with mannitol infusion (150 mg/ml; infusion rate of 0.5 ml/kg/h); MAP, mean arterial pressure; MPAP, mean pulmonary artery pressure; PCWP, pulmonary capillary wedge pressure; PVRI, pulmonary vascular resistance index; SVI, stroke volume index; SVRI, systemic vascular resistance index.