Skip to main content

Table 1

From: Low dose pentoxifylline (PTX) reduces mortality in an animal model of acute hepatic and multi-organ failure

          Mortality  
  AST (iu/l) PT (s) Ammonia (μg/ml) Lactate (mmol/l) (%)  
Hours 24 72 24 72 24 72 24 72 96  
G1-TAA 1553 ± 343 4512 ± 501 26 ± 3 121 ± 12 58 ± 8 134 ± 12 2.6 ± 1.2 6.3 ± 0.4 75
G2-PTX 300 mg/kg 2065 ± 330 5221 ± 528 >121* >121 117 ± 34* 153 ± 13 3.9 ± 0.5 7.8 ± 0.6 100*
G3-PTX 25 mg/kg 1177 ± 177 2021 ± 43* 23 ± 4 101 ± 13 71.4 ± 9 70.2 ± 10* 3.5 ± 0.1 4.6 ± 0.2* 40*
G4-Post PTX 25 mg/kg 2161 ± 166 5014 ± 299 >121 >121 121 ± 8* 156 ± 12 4.7 ± 0.6* 7.4 ± 0.8 100*
  1. *P < 0.05, mean ± SD.