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Table 1

From: Low dose pentoxifylline (PTX) reduces mortality in an animal model of acute hepatic and multi-organ failure

         

Mortality

 
 

AST (iu/l)

PT (s)

Ammonia (μg/ml)

Lactate (mmol/l)

(%)

 

Hours

24

72

24

72

24

72

24

72

96

 

G1-TAA

1553 ± 343

4512 ± 501

26 ± 3

121 ± 12

58 ± 8

134 ± 12

2.6 ± 1.2

6.3 ± 0.4

75

G2-PTX 300 mg/kg

2065 ± 330

5221 ± 528

>121*

>121

117 ± 34*

153 ± 13

3.9 ± 0.5

7.8 ± 0.6

100*

G3-PTX 25 mg/kg

1177 ± 177

2021 ± 43*

23 ± 4

101 ± 13

71.4 ± 9

70.2 ± 10*

3.5 ± 0.1

4.6 ± 0.2*

40*

G4-Post PTX 25 mg/kg

2161 ± 166

5014 ± 299

>121

>121

121 ± 8*

156 ± 12

4.7 ± 0.6*

7.4 ± 0.8

100*

  1. *P < 0.05, mean ± SD.
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Critical Care

ISSN: 1364-8535