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Figure 7 | Critical Care

Figure 7

From: RETRACTED ARTICLE: Diacerhein attenuates the inflammatory response and improves survival in a model of severe sepsis

Figure 7

Effects of diacerhein treatment on proteins that reflect ER stress in the CLP rat. Representative blots show the PERK, eIF2α phosphorylation, and IRE-1 expression in liver (A), adipose tissue (B), and muscle (C) of sham and septic rats. Blots were stripped and reprobed with β-actin (lower panels) to confirm equal loading of proteins. Data are presented as mean ± SEM from six to eight rats per group. *P < 0.05 versus Sham/Vehicle; #P < 0.05 (Sepsis/Veh versus Sepsis/Dia). IB, immunoblot; Sham, Sham/Vehicle; Sham+Dia, Sham/Diacerhein; Sepsis, Sepsis/Vehicle; Sepsis+Dia, Sepsis/Diacerhein.

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Critical Care

ISSN: 1364-8535