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Table 6 Clinical course and complications

From: A perioperative infusion of sodium bicarbonate does not improve renal function in cardiac surgery patients: a prospective observational cohort study

 

Total cohort

Control - no bicarbonate

Intervention - bicarbonate

Significance, P-value

Number

584

304 (52.1%)

280 (47.9%)

 

Postoperative ventilation time, h

7 (7, 7)

7 (6, 8)

7 (7, 8)

0.234

Reintubation

46 (7.9%)

22 (7.2%)

24 (8.6%)

0.648

Tracheostomy

18 (3.1%)

8 (2.6%)

11 (3.6%)

0.677

Duration in ICU, h

23 (23, 24)

23 (22, 24)

24 (23, 24)

0.093

Duration in IMC, h

38 (27, 43)

27 (24, 42)

44 (36, 48)

0.0008

Duration in HDU, h

85 (73, 89)

83 (71, 88)

88 (72, 96)

0.026

Re-admission to ICU

19 (3.3%)

9 (3.0%)

10 (3.6%)

0.849

Need for CPR

10 (1.7%)

6 (2.0%)

4 (1.4%)

0.851

Reoperation

80 (13.7%)

45 (14.9%)

35 (12.5%)

0.492

MAC Score

    

1

54 (9.2%)

25 (8.2%)

29 (10.4%)

0.728

2

25 (4.3%)

14 (4.6%)

11 (3.9%)

 

3

10 (1.7%)

5 (1.6%)

5 (1.8%)

 

4

1 (0.2%)

0 (0.0%)

1 (0.4%)

 

Status upon discharge from hospital

    

Extubated

551 (94.3%)

290 (95.4%)

261 (93.2%)

0.377

Intubated

10 (1.7%)

2 (0.7%)

8 (2.9%)

 

Tracheostomy

13 (2.2%)

7 (2.3%)

6 (2.1%)

 

Died in hospital

8 (1.4%)

4 (1.3%)

4 (1.4%)

 

Status after 30 days

    

Dead

11 (1.9%)

5 (1.6%)

6 (2.1%)

0.573

Alive

572 (97.9%)

298 (98.0%)

274 (97.9%)

 

Unknown

1 (0.2%)

1 (0.3%)

0 (0.0%)

 
  1. Postoperative course, complications, and clinical outcomes are shown in patients undergoing elective on-pump cardiac surgery with or without a perioperative infusion of bicarbonate. CPR: cardiopulmonary resuscitation; MAC score: 1 point for each of the following complications - low cardiac output syndrome, stroke, new need for renal replacement therapy, reintubation; IMC: intermediate care unit; HDU: high dependency unit. Data are given as absolute numbers (percentage) for nominal variables, median (95% confidence interval) for non-normally distributed data, and mean (95% confidence interval ) for normally distributed variables.