Skip to main content

Table 6 Clinical course and complications

From: A perioperative infusion of sodium bicarbonate does not improve renal function in cardiac surgery patients: a prospective observational cohort study

  Total cohort Control - no bicarbonate Intervention - bicarbonate Significance, P-value
Number 584 304 (52.1%) 280 (47.9%)  
Postoperative ventilation time, h 7 (7, 7) 7 (6, 8) 7 (7, 8) 0.234
Reintubation 46 (7.9%) 22 (7.2%) 24 (8.6%) 0.648
Tracheostomy 18 (3.1%) 8 (2.6%) 11 (3.6%) 0.677
Duration in ICU, h 23 (23, 24) 23 (22, 24) 24 (23, 24) 0.093
Duration in IMC, h 38 (27, 43) 27 (24, 42) 44 (36, 48) 0.0008
Duration in HDU, h 85 (73, 89) 83 (71, 88) 88 (72, 96) 0.026
Re-admission to ICU 19 (3.3%) 9 (3.0%) 10 (3.6%) 0.849
Need for CPR 10 (1.7%) 6 (2.0%) 4 (1.4%) 0.851
Reoperation 80 (13.7%) 45 (14.9%) 35 (12.5%) 0.492
MAC Score     
1 54 (9.2%) 25 (8.2%) 29 (10.4%) 0.728
2 25 (4.3%) 14 (4.6%) 11 (3.9%)  
3 10 (1.7%) 5 (1.6%) 5 (1.8%)  
4 1 (0.2%) 0 (0.0%) 1 (0.4%)  
Status upon discharge from hospital     
Extubated 551 (94.3%) 290 (95.4%) 261 (93.2%) 0.377
Intubated 10 (1.7%) 2 (0.7%) 8 (2.9%)  
Tracheostomy 13 (2.2%) 7 (2.3%) 6 (2.1%)  
Died in hospital 8 (1.4%) 4 (1.3%) 4 (1.4%)  
Status after 30 days     
Dead 11 (1.9%) 5 (1.6%) 6 (2.1%) 0.573
Alive 572 (97.9%) 298 (98.0%) 274 (97.9%)  
Unknown 1 (0.2%) 1 (0.3%) 0 (0.0%)  
  1. Postoperative course, complications, and clinical outcomes are shown in patients undergoing elective on-pump cardiac surgery with or without a perioperative infusion of bicarbonate. CPR: cardiopulmonary resuscitation; MAC score: 1 point for each of the following complications - low cardiac output syndrome, stroke, new need for renal replacement therapy, reintubation; IMC: intermediate care unit; HDU: high dependency unit. Data are given as absolute numbers (percentage) for nominal variables, median (95% confidence interval) for non-normally distributed data, and mean (95% confidence interval ) for normally distributed variables.