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Table 4 Intraoperative and postoperative hemodynamics

From: A perioperative infusion of sodium bicarbonate does not improve renal function in cardiac surgery patients: a prospective observational cohort study

  Total cohort Control - no bicarbonate Intervention - bicarbonate Significance, P-value
Number of patients 584 304 280  
HR, bpm, preoperative 68 (67, 70) 68.5 (67, 70) 68 (67, 70) 0.875
MAP, mmHg, preoperative 96 (95, 98) 97 (95, 100) 95 (93, 97) 0.396
MAP, mmHg, before induction 85 (82, 85) 87 (85, 90) 80 (76, 83) < 0.0001
MAP, mmHg, 30 minutes before CPB 70 (70, 71) 70 (70, 72) 70 (68, 71) 0.135
MAP, mmHg, 30 minutes after CPB 69 (68, 70) 70 (69, 71) 69 (67, 70) 0.109
MAP, mmHg, end of surgery 72 (71, 73) 73 (71, 74) 71 (70, 73) 0.150
MAP, mmHg, ICU admission 76 (75, 77) 76 (75, 78) 75 (73, 78) 0.339
MAP, mmHg, 2 h after ICU admission 73 (72, 74) 73 (71, 75) 73 (72, 74) 0.833
MAP, mmHg, 4 h after ICU admission 74 (72, 75) 74 (72, 76) 73 (72, 74) 0.541
MAP, mmHg, 6 h after ICU admission 73 (73, 74) 74 (73, 75) 73 (72, 75) 0.361
MAP, mmHg, 8 h after ICU admission 74 (73, 75) 74 (72, 75) 74 (72, 75) 0.632
CVP, mmHg, after induction 11 (10, 11) 11 (10, 11) 11 (10, 12) 0.340
CVP, mmHg, 30 minutes before CPB 8 (8, 8) 8 (8, 9) 8 (7, 9) 0.561
CVP, mmHg, 30 minutes after CPB 11 (10, 11) 10 (10, 11) 11 (10, 12) 0.663
CVP, mmHg, end of surgery 12 (11, 12) 12 (11, 12) 12 (11, 12) 0.396
CVP, mmHg, ICU admission 15 (15, 16) 16 (15, 16) 15 (15, 16) 0.689
CVP, mmHg, 2 h after ICU admission 15 (15, 16) 16 (15, 16) 15 (14, 15) 0.129
CVP, mmHg, 4 h after ICU admission 15 (15, 16) 15 (14, 16) 15 (15, 16) 0.425
CVP, mmHg, 6 h after ICU admission 14 (14, 15) 14 (14, 15) 14 (14, 15) 0.358
CVP, mmHg, 8 h after ICU admission 13 (13, 14) 13 (12, 14) 13 (12, 14) 0.801
MPAP, mmHg, After induction 25 (24, 27) 26 (24, 29) n = 61 25 (22, 29) n = 46 0.380
MPAP, mmHg, 30 minutes after CPB 25 (23, 27) 26 (23, 28) n = 76 25 (22, 27) n = 75 0.466
MPAP, mmHg, 30 minutes after CPB 26 (24, 27) 25 (23, 28) n = 104 26 (24, 28) n = 97 0.324
MPAP, mmHg, end of surgery 26 (25, 28) 26 (24, 28) n = 107 27 (24, 29) n = 94 0.659
MPAP, mmHg, ICU admission 29 (28, 30) 30 (29, 33) n = 113 27 (26, 29) n = 84 0.006
MPAP, mmHg, 2 h after ICU admission 30 (29, 31) 30 (29, 31) n = 120 29 (28, 31) n = 104 0.538
MPAP, mmHg, 4 h after ICU admission 30 (29, 31) 31 (29, 32) n = 126 29 (28, 30) n = 107 0.448
MPAP, mmHg, 6 h after ICU admission 29 (27, 29) 29 (27, 30) n = 125 28 (27, 30) n = 109 0.892
MPAP, mmHg, 8 h after ICU admission 28 (27, 29) 28 (26, 30) n = 128 28 (26, 30) n = 113 0.731
CI, L/min/m2, after induction 2.45 (2.24, 2.66) 2.46 (2.14, 2.77) n = 56 2.44 (2.17, 2.71) n = 38 0.947
CI, L/min/m2, 30 minutes before CPB 2.68 (2.57, 2.80) 2.62 (2.45, 2.79) n = 76 2.75 (2.58, 2.92) n = 75 0.269
CI, L/min/m2, 30 minutes after CPB 3.22 (3.08, 3.37) 3.14 (2.94, 3.34) n = 104 3.31 (3.09, 3.53) n = 97 0.261
CI, L/min/m2, end of surgery 3.02 (2.92-3.13) 2.95 (2.79, 3.11) n = 107 3.11 (2.97, 3.25) n = 94 0.140
CI, L/min/m2, ICU admission 2.80 (2.69, 2.92) 2.87 (2.73, 3.01) n = 113 2.71 (2.52, 2.89) n = 84 0.171
CI, L/min/m2, 2 h after ICU admission 3.06 (2.95, 3.17) 3.07 (2.92, 3.22) n = 120 3.05 (2.88, 3.21) n = 104 0.835
CI, L/min/m2, 4 h after ICU admission 3.12 (3.02, 3.23) 3.10 (2.98, 3.23) n = 126 3.15 (2.98, 3.32) n = 107 0.675
CI, L/min/m2, 6 h after ICU admission 3.24 (3.14, -3.35) 3.22 (3.10, 3.34) n = 125 3.27 (3.08, 3.46) n = 109 0.686
CI, L/min/m2, 8 h after ICU admission 3.18 (3.09, 3.28) 3.23 (3.11, 3.35) n = 128 3.13 (2.98, 3.28) n = 113 0.301
SvO 2 , %, after induction (n = 118) 79 (77, 80) 79 (78, 81) n = 61 77 (75, 79) n = 46 0.060
SvO 2 , %, 30 minutes before CPB (n = 147) 82 (81, 82) 82 (81, 83) n = 76 81 (80, 82) n = 75 0.357
SvO 2 , %, 30 minutes after CPB (n = 177) 78 (77, 79) 79 (77, 80) n = 104 78 (77, 80) n = 97 0.735
SvO 2 , %, end of surgery (n = 179) 77 (76, 78) 77 (76, 79) n = 107 77 (76, 79) n = 94 0.988
SvO 2 , %, ICU admission (n = 192) 71 (70, 72) 71 (70, 73) n = 113 70 (68, 72) n = 84 0.380
SvO 2 , %, 2 h after ICU admission (n = 287) 69 (68, 70) 69 (67, 70) n = 120 69 (67, 70) n = 104 0.931
SvO 2 , % 4 h after ICU admission (n = 309) 68 (67, 69) 67 (66, 69) n = 126 68 (67, 69) n = 107 0.322
SvO 2 , %, 6 h after ICU admission (n = 316) 69 (68, 70) 69 (68, 70) n = 125 69 (67, 70) n = 109 0.587
SvO 2 , %, 8 h after ICU admission 69 (68, 70) 69 (68, 71) n = 128 69 (67, 70) n = 113 0.264
  1. Data are given as median/mean (95% confidence interval for the median/mean) as appropriate. HR: heart rate; MAP mean arterial blood pressure; CVP: central venous pressure; MPAP: mean pulmonary arterial pressure; CI: cardiac index; SvO2: mixed venous oxygen saturation. MPAP, CI, and SvO2 were not available in every patient.
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