| |
Total cohort
|
Control - no bicarbonate
|
Intervention - bicarbonate
|
Significance, P-value
|
|---|
|
Number
|
584
|
304 (52.1%)
|
280 (47.9%)
| |
|
Type of procedure
| | | | |
|
CABG
|
222 (38.1)
|
110 (36.3%)
|
112 (40.0%)
|
0.160
|
|
Valve surgery +/- varia
|
176 (30.1%)
|
93 (30.7%)
|
82 (28.9%)
| |
|
CABG +/- valve +/- varia
|
120 (20.6%)
|
71 (23.4%)
|
49 (17.5%)
| |
|
Aortic surgery +/- valve +/- varia
|
54 (9.3%)
|
21 (6.9%)
|
33 (11.8%)
| |
|
Various procedures
|
10 (1.7%)
|
8 (2.6%)
|
3 (1.1%)
| |
|
Aortic surgery +/- CABG
|
2 (0.3%)
|
1 (0.3%)
|
1 (0.4%)
| |
|
Duration of surgery, minutes
|
254 (247, 261)
|
249 (242, 260)
|
258 (250, 268)
|
0.406
|
|
Duration of CPB, minutes
|
115 (110, 119)
|
115 9 (107, 122)
|
115 (109, 120)
|
0.756
|
|
Crossclamp time, minutes
|
89.5 (84, 93)
|
88.5 (82, 93)
|
90 (83, 96)
|
0.539
|
|
ECLS
|
7 (1.2%)
|
3 (1.0%)
|
4 (1.4%)
|
0.913
|
|
IABP
| | | | |
|
No IABP
|
556 (95.2%)
|
289 (95.1%)
|
267 (95.4%)
|
0.445
|
|
IABP before CPB
|
6 (1.0%)
|
2 (0.7%)
|
4 (1.4%)
| |
|
IABP during CPB
|
8 (1.4%)
|
6 (2.0%)
|
2 (0.7%)
| |
|
IABP after CPB
|
8 (1.4%)
|
3 (1.0%)
|
5 (1.8%)
| |
|
IABP on ICU
|
6 (1.0%)
|
4 (1.3%)
|
2 (0.7%)
| |
|
Circulatory arrest
|
21 (3.6%)
|
13 (4.3%)
|
8 (2.9%)
|
0.485
|
|
Lowest body temperature, °C
|
32 (32, 32)
|
32 (32, 32)
|
32 (32, 32)
|
0.615
|
- Surgical procedures and surgical core data are shown for patients undergoing elective on-pump cardiac surgery with or without a perioperative infusion of bicarbonate. CABG: coronary artery bypass grafting; CPB: cardiopulmonary bypass; ECLS: extracorporeal life support; IABP: intra-aortic balloon pump. Data are given as absolute numbers (percentage) for nominal variables and as median (95% confidence interval).
