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Table 3 Hemodynamics and catecholamine support according to outcome

From: Interleukin-6 is the strongest predictor of 30-day mortality in patients with cardiogenic shock due to myocardial infarction

 

All patients(n = 87)

Survivors(n = 59)

Nonsurvivors(n = 28)

P value

Hemodynamics

    

CI (L/min/m2)

2.15 ± 0.83

2.16 ± 0.78

2.12 ± 0.93

0.825

CPI (W/m2)

0.35 ± 0.15

0.37 ± 0.15

0.30 ± 0.15

0.041

CPO (W)

0.67 ± 0.26

0.70 ± 0.27

0.60 ± 0.25

0.102

Microcirculatory PI

97.51 ± 46.17

101.74 ± 43.08

86.23 ± 53.22

0.181

SV (ml)

52.6 ± 16.5

54.7 ± 16.8

48.1 ± 15.4

0.078

SVI (ml/m2)

26.8 ± 9.4

28.0 ± 9.0

24.3 ± 9.8

0.105

SW (g m)

37.5 ± 18.5

39.4 ± 18.6

31.7 ± 17.5

0.121

SWI (g m/m2)

19.1 ± 10.2

20.2 ± 10.1

16.0 ± 10.2

0.137

LVW (kg m/min)

2.88 ± 1.35

2.97 ± 1.35

2.60 ± 1.37

0.327

LVWI (kg m/min/m2)

1.47 ± 0.77

1.53 ± 0.74

1.30 ± 0.84

0.320

SVR (dynes sec/cm5)

1,251.8 ± 672.9

1,285.3 ± 705.6

1,146.6 ± 566.9

0.444

SVRI (dynes sec/cm5/m2)

2,281.6 ± 898.2

2,302.9 ± 894.2

2,216.2 ± 938.8

0.756

MAP (mm Hg)

71.1 ± 15.0

74.8 ± 13.7

63.8 ± 14.9

0.002

Min. MAP (mm Hg) day 1

55.1 ± 13.1

58.9 ± 10.9

45.8 ± 13.7

0.001

Systolic BP (mm Hg)

94.8 ± 22.7

98.6 ± 21.7

85.5 ± 23.0

0.036

Min. systolic BP (mm Hg) day 1

70.9 ± 17.7

75.8 ± 15.7

59.0 ± 16.8

0.001

LVEDP (mm Hg)

23.1 ± 8.9

22.9 ± 9.3

23.7 ± 8.1

0.748

CVP (mm Hg)

12.7 ± 5.8

12.2 ± 5.0

13.8 ± 7.6

0.416

Max. CVP (mm Hg) day 1

19.0 ± 8.3

17.2 ± 7.4

23.9 ± 8.9

0.008

HR (beats/min)

82.1 ± 21.2

78.7 ± 19.4

89.4 ± 23.2

0.043

Min. HR (beats/min) day 1

59.0 ± 17.3

56.4 ± 13.7

65.5 ± 23.3

0.115

Max. HR (beats/m) day 1

123.2 ± 25.3

118.8 ± 23.8

134.0 ± 26.2

0.032

Scvo2 (%)

66.3 ± 16.9

67.6 ± 16.5

63.2 ± 18.0

0.378

Min. Scvo2 (%) day 1

56.3 ± 13.5

56.2 ± 12.4

56.7 ± 16.3

0.905

Inotropic and vasopressor support

    

Catecholamine use (%)

68 (78.2%)

43 (72.9)

25 (89.3)

0.101

Dobutamine use (%)

52 (59.8)

33 (55.9)

20 (71.4)

0.240

Mean dose of dobutamine (µg/min) day 1

500 (0/975)

250 (0/700)

950 (0/1,075)

0.021

Norepinephrine use (%)

64 (73.6)

39 (66.1)

25 (89.3)

0.036

Mean dose of nor-epinephrine (µg/min) day 1

10 (0/61)

3 (0/15)

100 (40/130)

<0.0001

Epinephrine use (%)

25 (28.7)

8 (13.6)

18 (64.3)

<0.0001

Mean dose of epinephrine (µg/min) day 1

0 (0/0.5)

0 (0/0)

15 (0/80)

<0.0001

Total number of catecholamines

2.0 (1.0/2.0)

2.0 (0.0/2.0)

3.0 (2.0/3.0)

0.001

Total mean dose of catecholamines (µg/min) day 1

503 (0.6/1013)

305 (0/706)

995 (165/1310)

0.006

  1. Values are expressed as n (%), mean ± SD, or median with interquartile range (quartile 1 to quartile 3). Beats/min, beats per minute; BP, blood pressure; CI, cardiac index; CO, cardiac output; CPI, cardiac power index; CPO, cardiac power output; CVP, central venous pressure; HR, heart rate; LVEDP, left ventricular end-diastolic pressure; LVW, left ventricular work; LVWI, left ventricular work index; MAP, mean arterial pressure; max, maximal; min, minimal; Scvo2, central venous oxygen saturation; SV, stroke volume; SVI, stroke volume index; SVR, systemic vascular resistance; SVRI, systemic ventricular resistance index; SW, stroke work; SWI, stroke work index.
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Critical Care

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