Table 4 Positive predictive value (PPV) and negative predictive value (NPV) for assessing the prognostic utility of the average cfDNA, average MODS, and average protein C
From: Prognostic utility and characterization of cell-free DNA in patients with severe sepsis
Variable | Positive predictive value | 95% CI | Likelihood ratio χ2 | Negative predictive value | 95% CI | Likelihood ratio χ2 |
|---|---|---|---|---|---|---|
cfDNA | 0.84 | 0.72-0.96 | 18.49 | 0.93 | 0.85-1.00 | 37.85 |
MODS | 0.70 | 0.54-0.86 | 5.26 | 0.77 | 0.64-0.89 | 14.01 |
Protein C | 0.74 | 0.54-0.94 | 4.44 | 0.67 | 0.55-0.79 | 7.38 |
cfDNA and MODS | 0.91 | 0.81-1.00 | 26.84 | 0.93 | 0.86-1.00 | 41.59 |
cfDNA and protein C | 0.92 | 0.82-1.00 | 29.25 | 0.98 | 0.93-1.00 | 51.45 |