Table 5 Characteristics of the 196 Swedish patients stratified according to four degrees of severity by APACHE II score and serum suPAR
APACHE II <17 + suPAR <12 ng/mL | APACHE II <17 + suPAR ≥12 ng/mL | APACHE II ≥17 + suPAR <12 ng/mL | APACHE II ≥17 + suPAR ≥12 ng/mL | P value | |
|---|---|---|---|---|---|
Male/female | 28/21 | 11/10 | 33/28 | 36/29 | 0.986 |
Age in years, mean ± SD | 56.3 ± 16.9 | 54.3 ±19.1 | 64.2 ± 14.9 | 64.1 ± 13.0 | <0.0001 |
Sepsis stage, number (percentage) | 0.015 | ||||
Sepsis | 2 (4.1) | 0 (0) | 0 (0) | 0 (0) | |
Severe sepsis | 11 (22.4) | 10 (47.6) | 11 (18.0) | 11 (16.9) | |
Septic shock | 36 (73.5) | 11 (52.3) | 50 (82.0) | 54 (83.1) | |
Underlying infections, number (percentage) | 0.008 | ||||
CAP | 10 (20.5) | 4 (19.1) | 12 (19.6) | 13 (20.0) | |
HAP | 2 (4.1) | 1 (5.2) | 7 (11.5) | 8 (12.3) | |
VAP | 0 (0) | 0 (0) | 1 (1.6) | 0 (0) | |
UTI | 1 (2.0) | 3 (14.3) | 8 (13.1) | 12 (18.5) | |
IAI | 35 (71.5) | 15 (71.4) | 33 (54.1) | 26 (40) | |
BSI | 0 (0) | 0 (0) | 0 | 6 (9.2) | |
Underlying conditions, number (percentage) | 0.049 | ||||
COPD | 5 (10.2) | 0 (0) | 3 (4.9) | 6 (9.2) | |
DM2 | 9 (18.4) | 2 (9.5) | 11 (18.0) | 10 (15.4) | |
Heart failure | 4 (8.2) | 2 (9.5) | 8 (13.1) | 6 (9.2) | |
CRD | 0 (0) | 0 (0) | 2 (3.3) | 7 (10.8) | |
Malignancy | 16 (32.6) | 6 (28.6) | 21 (32.3) | 26 (40.0) |