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Table 1 Step-wise Cox regression analysis of factors related to unfavorable outcome in the study cohort of 1,914 Greek patients

From: Risk assessment in sepsis: a new prognostication rule by APACHE II score and serum soluble urokinase plasminogen activator receptor

Factor

Hazard ratio

95% CI

P value

Presence of severe sepsis/shock

1.46

1.32-1.61

<0.0001

At least one underlying diseasea

1.78

1.39-2.28

<0.0001

APACHE II score ≥17

4.24

3.30-5.43

<0.0001

Serum suPAR ≥12 ng/mL

1.62

1.30-2.00

<0.0001

  1. aChronic obstructive pulmonary disorder, diabetes mellitus type 2, chronic renal disease, heart failure, solid tumor malignancy, and chronic intake of corticosteroids. APACHE II, Acute Physiology and Chronic Health Evaluation II; CI, confidence interval; suPAR, soluble urokinase plasminogen activator receptor.