Table 2 Studies comparing manual hyperinflation (MH) with other strategies
Author [ref] | Year | Subjects | N | Study design | Intervention | Reported aspects of the MH maneuver | Main results |
|---|---|---|---|---|---|---|---|
Berney et al. [29] | 2002 | Unselected intensive care unit patients | 20 | Randomized crossover trial | MH vs. hyperinflation by the mechanical ventilator | Volume: ± Inspiration speed: + Pause: + Expiration speed: ± | Both techniques improved pulmonary compliance equally; no affects on clearance of airway secretions |
Paratz et al. [33] | 2002 | Patients with acute lung injury | 16 | Prospective observational study | MH | Volume: + Inspiration speed: + Pause: + Expiration speed: + | MH increased pulmonary compliance; P/F increased in patients with an extrapulmonary cause of acute lung injury, whereas it decreased in patients with a pulmonary cause of acute lung injury |
Savian et al. [30] | 2006 | Unselected intensive care unit patients | 14 | Randomized crossover trial | MH vs. hyperinflation by the mechanical ventilator | Volume: - Inspiration speed: + Pause: + Expiration speed: + | MH affected neither pulmonary compliance and PaO2, nor clearance of airway secretions |
Hodgson et al. [31] | 2007 | Unselected intensive care unit patients | 20 | Randomized crossover trial | MH with two different devices for hyperinflation | Volume: ± Inspiration speed: - Pause: + Expiration speed: ± | MH affect neither pulmonary compliance nor P/F; clearance of airway secretions differed between two devices |
Ahmed et al. [28] | 2010 | Postcardiac surgery patients | 30 | Randomized controlled trial | MH vs. hyperinflation by the mechanical ventilator | Volume: ± Inspiration speed: + Pause: + Expiration speed: + | Both techniques improved P/F equally; both techniques did not affect pulmonary compliance |
Dennis et al. [27] | 2012 | Patients with atelectasis | 46 | Randomized cross-over trial | MH vs. hyperinflation by the mechanical ventilator | Volume: ± Inspiration speed: - Pause: + Expiration speed: - | Clearance of airway secretions did not differ between the two techniques; both techniques did not affect pulmonary compliance; P/F increased after VH but it decreased after MH |