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Table 3 BALF, serum GM and Aspergillus isolation from LRT.

From: Role of galactomannan determinations in bronchoalveolar lavage fluid samples from critically ill patients with chronic obstructive pulmonary disease for the diagnosis of invasive pulmonary aspergillosis: a prospective study

  BALF GM ( 95%CI)
(cut-off 0.8)
BALF GM ( 95%CI)
(cut-off 0.5)
Serum GM ( 95%CI)
(cut-off 0.5)
Isolation of Aspergillus from LRT ( 95%CI)
Sensitivity (%) 66.7 (48.6 to 84.8) 73.3 (56.3 to 90.3) 53.3 (34.1 to 72.5) 46.7 (27.5 to 65.9)
Specificity (%) 100 (100 to 100) 52.6 (33.4 to 71.8) 100 (100 to 100) 89.5 (77.7 to 101.3)
PPV (%) 100 (100 to 100) 55.0 (35.9 to 74.1) 100 (100 to 100) 77.8 (61.8 to 93.8)
NPV (%) 79.1 (63.5 to 94.7) 71.4 (54.0 to 88.8) 73.0 (55.9 to 90.1) 68.0 (50.1 to 85.9)
TCR (%) 85.3 (71.7 to 98.9) 61.8 (43.1 to 80.5) 79.4 (63.9 to 94.9) 70.6 (53.1 to 88.1)
  1. For probable, possible IPA, colonization and control patients (n = 34).
  2. BALF, bronchoalveolar lavage fluid; CI, confidence interval; COPD, chronic obstructive pulmonary disease; GM, galactomannan; IPA, invasive pulmonary aspergillosis; LRT, lower respiratory tract; NPV, negative predictive value; PPV, positive predictive value; TCR, total consistent rate.