Table 3 Operating characteristics of sST2 for predicting response to pulmonary artery catheter guided therapy
Outcome and cut-off point | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|
CVP non-response | Â | Â | Â | Â |
   129 ng/mL (median) | 83% | 67% | 63% | 86% |
   171 ng/mL (ROC optimal) | 83% | 78% | 71% | 88% |
PCWP non-response | Â | Â | Â | Â |
   129 ng/mL (median) | 67% | 67% | 75% | 57% |
   98 ng/mL (ROC optimal) | 89% | 58% | 76% | 78% |
SVR non-response | Â | Â | Â | Â |
   129 ng/mL (median) | 57% | 50% | 50% | 57% |
   105 ng/mL (ROC optimal) | 71% | 47% | 53% | 64% |