Table 3 Failure of noninvasive mechanical ventilation
From: Ventilatory support in critically ill hematology patients with respiratory failure
Univariate comparison | Logistic regression | |||||
|---|---|---|---|---|---|---|
NIV success n= 52 | NIV failure n= 79 | Pvalue (univariate) | OR | 95% confidence interval | Pvalue | |
Age, years (SD) | 58.1 (12.1) | 50.4 (18.1) | 0.004 | 0.958 | 0.932-0.985 | 0.002 |
Women (%) | 22 (42) | 23 (29) | 0.13 | |||
APACHE II (SD) | 22.3 (6.3) | 23.7 (8.5) | 0.37 | |||
Main diagnosis (%) | 0.07 | |||||
Acute leukemia | 25 (48) | 28 (35.4) | 0.606 | 0.133-2.753 | 0.52 | |
Chronic leukemia | 4 (7.6) | 14 (17.7) | 3.482 | 0.531-22.834 | 0.19 | |
Hodgkin lymphoma | 2 (3.8) | 6 (7.6) | 2.495 | 0.241-25.835 | 0.44 | |
Non-Hodgkin lymphoma | 10 (19.2) | 22 (27.8) | 1.451 | 0.291-7.237 | 0.65 | |
Multiple myeloma | 6 (11.5) | 2 (2.5) | 0.245 | 0.028-2.170 | 0.21 | |
Myelodysplastic syndrome | 1 (1.9) | 0 (0) | ||||
Other | 0 (0) | 1 (1.3) | ||||
HSCT (%) | 0.60 | |||||
No | 39 (75) | 62 (78.5) | ||||
Autologous | 8 (15.4) | 13 (16.4) | ||||
Allogeneic | 5 (9.6) | 4 (5.1) | ||||
Neutropenia (%) | 24 (42) | 33 (58) | 0.54 | |||
Diagnosis on ICU admission (%) | ||||||
Shock | 12 (23) | 13 (16.5) | 0.37 | |||
Infection (other than pneumonia) | 33 (63) | 56 (70.9) | 0.44 | |||
Pneumonia | 20 (50) | 38 (63.3) | 0.28 | |||
Other causes of respiratory failure | 12 (30.7) | 26 (22.8) | 0.22 | |||
Congestive heart failure | 10 (19.2) | 4 (5.1) | 0.02 | 0.162 | 0.034-0.780 | 0.02 |
Coma | 1 (1.9) | 0 (0) | ||||
Other | 3 (5.8) | 8 (10.1) | 0.38 | |||
Bacteremia on admission (%) | 22 (42.3) | 19 (24.1) | 0.03 | 0.422 | 0.179-0.997 | 0.05 |