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Table 3 Failure of noninvasive mechanical ventilation

From: Ventilatory support in critically ill hematology patients with respiratory failure

  Univariate comparison Logistic regression
  NIV success
n= 52
NIV failure
n= 79
Pvalue
(univariate)
OR 95% confidence interval Pvalue
Age, years (SD) 58.1 (12.1) 50.4 (18.1) 0.004 0.958 0.932-0.985 0.002
Women (%) 22 (42) 23 (29) 0.13    
APACHE II (SD) 22.3 (6.3) 23.7 (8.5) 0.37    
Main diagnosis (%)    0.07    
   Acute leukemia 25 (48) 28 (35.4)   0.606 0.133-2.753 0.52
   Chronic leukemia 4 (7.6) 14 (17.7)   3.482 0.531-22.834 0.19
   Hodgkin lymphoma 2 (3.8) 6 (7.6)   2.495 0.241-25.835 0.44
   Non-Hodgkin lymphoma 10 (19.2) 22 (27.8)   1.451 0.291-7.237 0.65
   Multiple myeloma 6 (11.5) 2 (2.5)   0.245 0.028-2.170 0.21
   Myelodysplastic syndrome 1 (1.9) 0 (0)     
   Other 0 (0) 1 (1.3)     
HSCT (%)    0.60    
   No 39 (75) 62 (78.5)     
   Autologous 8 (15.4) 13 (16.4)     
   Allogeneic 5 (9.6) 4 (5.1)     
Neutropenia (%) 24 (42) 33 (58) 0.54    
Diagnosis on ICU admission (%)       
   Shock 12 (23) 13 (16.5) 0.37    
   Infection (other than pneumonia) 33 (63) 56 (70.9) 0.44    
   Pneumonia 20 (50) 38 (63.3) 0.28    
   Other causes of respiratory failure 12 (30.7) 26 (22.8) 0.22    
   Congestive heart failure 10 (19.2) 4 (5.1) 0.02 0.162 0.034-0.780 0.02
   Coma 1 (1.9) 0 (0)     
   Other 3 (5.8) 8 (10.1) 0.38    
Bacteremia on admission (%) 22 (42.3) 19 (24.1) 0.03 0.422 0.179-0.997 0.05
  1. Univariate comparisons between patients with NIMV success and NIMV failure, and results of the logistic regression analysis. Values are given as number (%) or mean (SD).