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Figure 3 | Critical Care

Figure 3

From: Identification of haplotype tag single nucleotide polymorphisms within the receptor for advanced glycation end products gene and their clinical relevance in patients with major trauma

Figure 3

Effect of the -429T/C polymorphism on the transcription activity of the RAGE promoter. Relative luciferase activity (RLA) was measured in U937 cells transfected with -429T or -429C plasmid constructs as described in methods. The fold increase of RLA was significantly lower in cells transfected with variant C allele than those transfected with wild T allele (P = 0.032).

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Critical Care

ISSN: 1364-8535