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Table 2 Univariate analyses demonstrating the association of (A) free hemoglobin concentration and (B) age, SAPS II score, SOFA score, and procalcitonin with 30-day survival in severe sepsis.

From: Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome

A.

Median

Odds ratio

95% CI

Significance level

ELISA

0.037 g/l

2.33

1.17, 4.65

0.015

Harboe

0.068 g/l

6.06

2.79, 7.80

< 0.001

Noe

0.085 g/l

5.21

2.44, 11.11

< 0.001

Fairbanks

0.059 g/l

3.92

1.90, 8.06

< 0.001

B.

Median

Odds ratio

95% CI

Significance level

Age

57.0 y

1.22

0.63, 2.38

0.560

SAPS II score

47.5

1.92

0.98, 3.79

0.058

SOFA score

11.5

2.07

0.97, 4.43

0.058

Procalcitonin

3.385 ng/ml

1.42

0.68, 2.95

0.351

  1. Patients were grouped according to high and low free hemoglobin determined by the median of the respective value, measured by ELISA, and by the Harboe, Noe and Fairbanks methods [1315]. Thereafter, odds ratios for death in severe sepsis were determined. Depicted are the median of the respective value, the odds ratios, the 95% confidence intervals (95% CI), and the significance levels (Chi square test). SAPS II score: simplified acute physiology score II; SOFA score: sequential organ failure assessment score.