Kidney function decline after a non-dialysis-requiring acute kidney injury is associated with higher long-term mortality in critically ill survivors

Table 4 A multivariate Cox proportional hazards model for independent factors associated with the composite outcomes

Composite outcome	Covariate	HR (95% CI)	P
Stage 3 CKD or death	baseline eGFR	0.99 (0.98, 1.00)	0.02
(n = 187)	age	1.02 (1.00, 1.03)	0.02
Stage 4 CKD or death	received surgery	0.42 (0.25, 0.72)	0.002
(n = 374)	hypertension	0.56 (0.39, 0.80)	0.002
	baseline eGFR	0.99 (0.98, 1.00)	0.009
	age	1.04 (1.02, 1.06)	< 0.001
	SCr at the peak of AKI	1.20 (1.04, 1.38)	0.01
	diabetes	1.79 (1.25, 2.58)	0.002
	IABP	1.88 (1.14, 3.09)	0.01
Stage 5 CKD or death	organ transplantation	0.30 (0.09, 0.96)	0.04
(n = 421)	BMI	0.94 (0.90, 0.99)	0.02
	age	1.04 (1.03, 1.06)	< 0.001
	SCr at the peak of AKI	1.20 (1.05, 1.36)	0.006
	general surgical services	2.09 (1.45, 3.01)	< 0.001
	CPR	3.22 (1.36, 7.62)	0.008

AKI, acute kidney injury; BMI, body mass index; CI, confidence interval; CPR, cardiopulmonary resuscitation; eGFR, estimated glomerular filtration rate; HR, hazard ratio; IABP, intra-aortic balloon pump; SCr, serum creatinine.

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