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Table 3 Plasma concentrations of biomarkers and severity scores, by survival status

From: Pancreatic stone protein as an early biomarker predicting mortality in a prospective cohort of patients with sepsis requiring ICU management

Biomarker or severity scoring system All (n= 107)  
  Death ( n = 22) Survival ( n = 85)  
  Median IQR Median IQR P value
Acute-phase proteins      
   CRP, mg/L 203 188 266 154 0.21
   PCT, ng/mL 17.485 51.75 26.22 44.75 0.57
   PSP/reg, ng/mL 397 435.9 216.1 379 0.02
Cytokines      
   TNF-α, pg/ml 2.655 10.36 2.35 6.73 0.46
   IL-1β, pg/mL 0.795 34.02 7.6 20.41 0.46
   IL-6, pg/mL 2,415.58 16,219.42 790.53 6,467.74 0.16
   IL-8, pg/mL 757.775 10,597.73 414.88 1,597.6 0.11
   IL-10, pg/mL 416.18 1393.6 136.76 494.89 0.17
Other      
   Leukocytes, G/L 13.85 14.45 13.4 14.2 0.27
   APACHE II 32 12 27 13 0.4
   SAPS II 71.5 26 68 27 0.52
   SAPS III 87.5 27 74 25 0.01
   SOFA 11 6 11 4 0.9
  1. APACHE II, Acute Physiology and Chronic Health Evaluation II; CRP, C-reactive protein; IL, interleukin; IQR, interquartile range; PCT, procalcitonin; PSP/reg, pancreatic stone protein/regenerating protein; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment; TNF-α, tumor necrosis factor-alpha.