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Table 3 Main metabolic and electrolyte parameters throughout RCA-CVVH days.

From: Regional citrate anticoagulation in cardiac surgery patients at high risk of bleeding: a continuous veno-venous hemofiltration protocol with a low concentration citrate solution

  Days on RCA
  1 2 3 4 Last day
Systemic Ca++ (mmol/l) 1.2 (1.09-1.36) 1.2 (1.14-1.25) 1.19 (1.15-1.24) 1.16 (1.12-1.26) 1.19 (1.13-1.24)
Circuit Ca++ (mmol/l) 0.39 (0.33-0.43) 0.37 (0.31-0.4) 0.32 (0.28-0.37)** 0.35 (0.31-0.39) 0.34 (0.32-0.39)
Systemic sodium (mmol/l) 136 (134-139.2) 135 (133-138) 134 (132-138)* 134 (131.7-136)* 135 (134-136)
Estimated citrate load (mmol/hour) 11.3 (10.1-12.4) 11.3 (10.2-12.3) 11.3 (10.1-12.5) 11.3 (10.2-12.5) 10.7 (10.1-11.9)
Calcium Ratio 1.88 (1.78-2.04) 1.96 (1.87-2.04) 1.96 (1.84-2.1) 1.92 (1.82-2.1) 2 (1.89-2.08)
pH (units) 7.4 (7.35-7.43) 7.4 (7.36-7.42) 7.4 (7.34-7.43) 7.4 (7.35-7.43) 7.41 (7.37-7.43)
Systemic bicarbonates (mmol/l) 22.9 (20.6-23.9) 22 (20.9-22.8) 22 (20.7-23.2) 21.4 (20.2-23.3) 22 (20.4-23.2)
Base excess -3 (-4.7 to -1.1) -3.2 (-3.8 to -2) -3.1 (-4.1 to -2) -3 (-3.5 to -1.6) -2.5 (-4 to -1)
Systemic lactate (mmol/l) 1.3 (1-1.8) 1.2 (0.9-1.5) 1.05 (0.8-1.25) 1 (0.9-1.3) 1.1 (0.7-1.65)
  1. Data are expressed as median (interquartile range). All points of considered parameters were not significant, except for time day 3 versus day 1 of circuit Ca++ (** P < 0.02) and for time day 3 and 4 versus day 1 of systemic sodium (* P < 0.05). RCA-CVVH, regional citrate anticoagulation-continuous veno-venous hemofiltration.