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Table 1 Hemodynamic data (mean ± SEM)

From: Inhaled nitric oxide reverses cell-free hemoglobin-induced pulmonary hypertension and decreased lung compliance. Preliminary results

Variable Baseline ααHb NO 5 ppm OFF NO 10 ppm OFF
MAP (mmHg) 97 ± 3.9 119 ± 7.0 117 ± 9.7 120 ± 10.4 117 ± 7.7 116 ± 10.2
CVP (mmHg) 4.0 ± 1.5 6.5 ± 1.3 4.8 ± 1.4 4.9 ± 0.9 4.5 ± 1.9 4.8 ± 1.7
PAOP (mmHg) 9.6 ± 1.9 12.6 ± 1.7 11.2 ± 1.9 10.6 ± 1.5 10.4 ± 1.3 12.4 ± 2.5
HR (beats/min) 106 ± 3.9 88 ± 4.5 90 ± 7.6 92 ± 6.7 91 ± 5.6 95 ± 5.8
Cl (ml/min/m2) 4.7 ± 0.4 4.2 ± 0.1 3.5 ± 0.4 3.4 ± 0.5 3.7 ± 0.5 3.2 ± 0.5
SVRI (dyn s/cm5m2) 1603 ± 100 2152 ± 147 2952 ± 492 2952 ± 570 2655 ± 348 3286 ± 559
PVRI(dyn s/cm5m2) 291 ± 67 513 ± 92 485 ± 114 657 ± 139 396 ± 73 663 ± 146
SvO2(%) 93 ± 0.1 80 ± 4.3 78 ± 8.4 78 ± 7.8 77 ± 5.7 77 ± 7.9
  1. ααHb: αα-crosslinked hemoglobin 200 mg/kg; NO 5ppm = 5ppm inhaled nitric oxide; NO 10 ppm = 10 ppm inhaled nitric oxide; OFF = nitric oxide discontinued; MAP = mean arterial pressure; CVP = central venous pressure; PAOP = pulmonary artery occlusion pressure; HR = heart rate; CI = cardiac index; SVRI = systemic vascular resistance index; PVRI = pulmonary vasclar resistance index; SvO2 = mixed venous oxygen saturation *P<0.05 compared to baseline.