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Table 1 Definitions

From: Four hour creatinine clearance is better than plasma creatinine for monitoring renal function in critically ill patients

Name Abbreviation Calculation
Creatinine Clearance CCl (Urine creatinine concentration/Plasma creatinine concentration) × (Volume of urine collected over 4 hours in ml/(4 × 60))
Cockcroft-Gault clearance [17] CG [(140-Age in years) × weight in kg/(72 × Plasma creatinine concentration in mg/dl)] × 0.85 if female
Average urine output UO Volume of urine collected over 4 hours in ml/(4 × Patient weight in kg)
Change in CCl ΔCCl 100 × (Measured CG on entry - baseline CCl)/Baseline CG
Change in plasma creatinine ΔpCr 100 × (On entry creatinine - baseline creatinine)/Baseline creatinine
AKI plasma creatinine ΔpCrAKI ΔpCr > 50%
AKI creatinine clearance ΔCClAKI ΔCCl < -33.3%
AKI urine output (oliguria) UOAKI Urine output < 0.5 ml/kg/hr on average over 4 hours
RIFLE class R R ΔpCr > 50% and ≤ 100%, or ΔCCl < -33.3% and ≥ -50%
RIFLE class I I ΔpCr > 100% and ≤ 200%, or ΔCCl < -50% and ≥ -66.7%
RIFLE class F F ΔpCr > 200% or ΔCCl < -66.7%
AKI from entry (AKIN) AKIAKIN (Plasma creatinine - on entry plasma creatinine) > 0.3 mg/dl or 50% within 48 hours
  1. AKI: acute kidney injury; RIFLE: Risk, Injury, Failure, Loss, End stage.