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Table 1 Characteristics of the study patients according to infection status.

From: Assessment of candidemia-attributable mortality in critically ill patients using propensity score matching analysis

  Without candidemia
(number = 1,069)
With candidemia
(number = 38)
P value SDT
Age, years, mean (SD) 60.0 ± 17.1 59.0 ± 17.9 .706 5.7%
Male/female (%) 67.4/32.6 63.2/36.8 .583 8.8%
APACHE II score at ICU admission, mean (SD) 18.3 ± 7.0 20.1 ± 6.5 .131 -19.24%
SOFA score at ICU admission 7 (4 to 9) 8.5 (7 to 10) .004  
ICU length of stay (days)a 17 (12 to 28) 28.5 (16.5 to 53.5) .001  
Hospital length of stay (days)a 37 (23 to 59) 37 (26 to 67) .436  
ICU mortality, number (%) 220 (20.6) 20 (52.6)) < .001  
Overall mortality, number (%) 314 (29.6) 21 (55.3) .001  
Diagnosis on ICU admission, number (%)    .437  
   Medical 523 (48.9) 16 (42.1)   -13.68%
   Surgical 369 (34.5) 17 (44.7)   20.97%
   Trauma 177 (16.6) 5 (13.2)   -9.55
Multifocal colonization, total, number (%) 649 (60.7) 35 (92.1) < .001 79.58%
Clinical condition, number (%) at the time of ICU admission    < .001  
   No sepsis 497 (46.6) 1 (2.6)   -118.8%
   Sepsis 297 (27.9) 11 (28.9)   2.22%
   Severe sepsis 108 (10.1) 11 (28.9)   48.84%
   Septic shock 164 (15.4) 15 (39.5)   56.1%
Surgery, number (%) 369 (34.4) 17 (44.7) .202 21.18%
Abdominal surgery, number (%) 205 (19.2) 12 (31.6) .075 28.78%
Surgical procedures, number    .302  
   None 625 (58.5) 20 (52.6)   -11.89%
   One 316 (29.6) 10 (26.3)   -7.36%
   Two or more 128 (12.0) 8 (21.1)   24.67
Secondary peritonitis, number (%) 65 (6.1) 4 (10.5) .306 16%
Underlying illnesses, number (%)     
Neurologic disease 224 (21.0) 5 (13.2) .220 -20.83%
Trauma 197 (18.4) 7 (18.4) .999 0%
Diabetes mellitus 183 (17.1) 7 (18.4) .836 3.4%
COPD 163 (15.2) 9 (23.7) .183 21.6%
Heart failure 91 (8.5) 6 (15.8) .155 22.48%
Chronic renal failure 58 (5.4) 2 (5.3) .965 -0.44%
Acute coronary syndrome 51 (4.8) 1 (2.6) .507 -11.67%
Chronic liver failure 45 (4.2) 1 (2.6) .609 -8.84%
Hematologic malignancy 12 (1.1) 0 .359 -14.91%
Solid tumor 124 (11.6) 4 (10.5) .837 -3.51%
Risk factors, number (%)     
Urinary catheter 1,057 (99.1) 37 (97.4) .387 -12.99%
Central venous catheter 1,044 (97.8) 38 (100.0) .193 21.21%
Mechanical ventilation 967 (90.5) 37 (97.4) .097 29.24%
Broad-spectrum antibiotics 941 (88.3) 36 (97.3) .046 35.36%
Empiric/preemptive antifungal treatment. 180 (16.8) 2 (5.3) .032 -37.31%
Arterial catheter 846 (79.5) 37 (97.4) .001 58.33%
Enteral nutrition 825 (77.2) 26 (68.4) .225 -19.87%
Total parenteral nutrition 428 (40.4) 27 (71.1) < .001 64.99%
Corticosteroids 300 (28.5) 12 (31.6) .679 6.76%
Renal replacement therapy 126 (12.0) 15 (39.5) < .001 66.25%
  1. aMedian (25th to 75th percentiles). APACHE, Acute Physiology and Chronic Health Score; COPD, Chronic Obstructive Pulmonary Disease; SD, standard deviation; SDT, standardized difference; SOFA, Sequential Organ Failure Assessment.