Red cell distribution width improves the simplified acute physiology score for risk prediction in unselected critically ill patients

Table 3 Reclassification results for in-hospital and ICU mortality

	Hospital mortality				ICU mortality
	SAPS	SAPS and RDW	SAPS versus SAPS/RDW	P	SAPS	SAPS and RDW	SAPS versus SAPS/RDW	P
Model χ² (log likelihoods)	1,505	1,831	326	< 0.0001	1,539	1,664	124	< 0.0001
Area under the ROC curve	0.746	0.774	0.028	< 0.001	0.793	0.805	0.012	< 0.001
Events
Upward reclassification			362				197
No reclassification			1,214				947
Downward reclassification			309				153
No events
Upward reclassification			1,532				1,376
No reclassification			9,849				12,412
Downward reclassification			4,046				2257
Net reclassification improvement			0.175 (SE 0.015)	< 0.0001			0.090 (SE 0.049)	< 0.0001
Integrated sensitivity	0.20	0.23	0.021	< 0.0001	0.19	0.20	0.01	< 0.0001
Integrated specificity	0.099	0.096	-0.0026	< 0.0001	0.07	0.06	-0.0008	< 0.0001
Integrated discrimination improvement			0.023 (SE 0.001)	< 0.0001			0.011 (SE 0.001)	< 0.0001

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