Combining intermediate levels of the Endotoxin Activity Assay (EAA) with other biomarkers in the assessment of patients with sepsis: results of an observational study

Table 1 Characteristics of patients

	Low EAA (<0.40)	Intermediate EAA (0.4-0.59)	High EAA (≥0.6)	P value
Number	104	79	27
Age (range), years	67.5 (19-96)	71 (23-97)	76 (25-92)	0.59
Percentage of males	69.8	60	74	0.25
Body temperature (range), °C	37.0 (36.4-37.6)	37.2 (34-39.2)	37.3 (36-39.2)	0.51
White blood cells (IQR),/mm³	12,030 (8,720-18,150)	12,030 (7,080-17,053)	11,550 (2,522-15,888)	0.22
Stab neutrophils (IQR), percentage	9.0 (2.4-21.4)	7.5 (2.0-23.0)	10.0 (2.8-37.8)	0.45
Segmented neutrophils (IQR), percentage	78.5 (66.0-84.6)	78.0 (59.8-85.5)	71.0 (36.1- 84.8)	0.19
Left shift of neutrophils, percentage	37.7	36.3	44.4	0.77
C-reactive protein (IQR), mg/dL	11.6 (7.0-19.6)	12.2 (6.9-19.9)	13.2 (6.4-21.2)	0.06
Procalcitonin (IQR), ng/mL	1.0 (0.2-5.2)	1.7 (0.3-7.7)	4.7 (1.6-24.8)	0.003
Gram-negative organism, percentage	27.4	51.3	70.4	<0.0001
Gram-negative bacteremia, percentage	3.8	10	25.9	<0.0001
ICU mortality, percentage	17.3	22.5	37	0.13

EAA, Endotoxin Activity Assay; ICU, intensive care unit; IQR, interquartile range.

ISSN: 1364-8535