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Table 1 Study settings, size and quality of studies of fluid therapy

From: Clinical review: Volume of fluid resuscitation and the incidence of acute kidney injury - a systematic review

Author

Year

Country

Population

Number

Blinded

Randomised

Dropouts

Jadad score

Studies of GDT in surgery

Challand and colleagues [25]

2012

UK

Major open or laparoscopic colorectal surgery

179

1

2

1

4

Cecconi and colleagues [24]

2011

Italy

Elective total hip arthroplasty

40

1

2

1

3

Mayer and colleagues [35]

2010

Germany

Major abdominal surgery

60

1

2

1

3

Jhanji and colleagues [31]

2010

UK

Major gastrointestinal surgery

135

0

2

1

3

Forget and colleagues [28]

2010

Belgium

Major abdominal surgery

82

0

1

1

2

Benes and colleagues [21]

2010

Czech Republic

High-risk elective intra-abdominal surgery

120

1

2

1

4

Harten and colleagues [30]

2008

UK - Scotland

Patients over the age of 50 undergoing emergency abdominal surgery

29

0

2

1

3

Kapoor and colleagues [32]

2008

India

Patients with EuroSCORE ≥3 undergoing coronary artery bypass surgery under cardiopulmonary bypass

30

0

2

1

3

Donati and colleagues [27]

2007

Italy

Major abdominal surgery

135

0

2

1

3

Lopes and colleagues [34]

2007

Brazil

High-risk surgery

33

0

2

1

3

Chytra and colleagues [26]

2006

Czech Republic

ICU admissions undergoing surgery for major trauma with expected blood loss >2 l

162

0

1

1

2

Wakeling and colleagues [42]

2006

UK

Colorectal resection

128

0

2

1

3

Noblett and colleagues [37]

2006

UK

Elective colorectal resection

108

2

1

1

4

Pearse and colleagues [38]

2005

UK

High-risk general surgical patients

122

0

2

1

3

McKendry and colleagues [36]

2004

UK

Cardiac surgery

174

0

2

1

3

Gan and colleagues [29]

2002

USA

Major elective surgery with an anticipated blood loss >500 ml

100

0

2

1

3

Bonazzi and colleagues [23]

2002

Italy

Infrarenal abdominal aortic aneurysm repair

100

0

2

0

2

Venn and colleagues [41]

2002

UK

Proximal femoral fracture repair, age >65

90

0

2

1

3

Lobo and colleagues [33]

2000

Brazil

Patients >60 years old and/or with chronic diseases of vital organs who underwent major elective surgery

37

0

2

1

3

Pölönen and colleagues [39]

2000

Finland

Elective cardiac surgery

403

0

2

1

3

Wilson and colleagues [43]

1999

UK

Patients undergoing major elective surgery who were at risk of developing postoperative complications

138

0

2

1

3

Valentine and colleagues [40]

1998

USA

Aortic surgery

120

0

1

1

2

Bender and colleagues [20]

1997

USA

Elective vascular surgery

104

0

1

1

2

Bishop and colleagues [22]

1995

USA

Surgery for major trauma

125

0

1

1

2

Studies using GDT in surgery comparing restrictive vs. conservative maintenance fluids

Lobo and colleagues [46]

2011

Brazil

High-risk elective surgery

88

0

1

1

2

Futier and colleagues [44]

2011

France

Major abdominal surgery

70

1

2

1

4

Jammer and colleagues [45]

2010

Norway

Open colorectal and lower intestinal surgery

241

0

2

1

3

  1. GDT, goal-directed therapy