From: Early course of microcirculatory perfusion in eye and digestive tract during hypodynamic sepsis
Variables | Group | Baseline | 3 hours | 5 hours | ANOVA (P) |
---|---|---|---|---|---|
HR, beats/min | Sepsis | 85 ± 18 | 104 ± 34 | 101 ± 25 | 0.368 |
Sham | 84 ± 8 | 99 ± 12 | 98 ± 4 | 0.400 | |
MAP, mm Hg | Sepsis | 99 ± 17 | 80 ± 25 | 92 ± 29 | 0.417 |
Sham | 107 ± 18 | 113 ± 4 | 92 ± 5 | 0.607 | |
MPAP, mm Hg | Sepsis | 19 ± 6 | 36 ± 7a | 37 ± 6a | 0.022 |
Sham | 23 ± 9 | 21 ± 2 | 20 ± 5 | 0.867 | |
CI, L/min/m2 | Sepsis | 3.6 ± 0.8 | 2.4 ± 1.1a | 1.8 ± 0.6a | 0.028 |
Sham | 3.4 ± 0.1 | 4.2 ± 0.1 | 4.7 ± 2.0 | 0.368 | |
SVRI, dynes/sec/cm3 | Sepsis | 1,938 ± 350 | 3,304 ± 1,513a | 4,379 ± 1,640a | 0.007 |
Sham | 2,065 ± 12 | ,2081 ± 128 | 1,776 ± 404 | 0.607 | |
CVP, mm Hg | Sepsis | 6 ± 2 | 8 ± 3 | 7 ± 3 | 0.300 |
Sham | 5 ± 1 | 4 ± 1 | 3 ± 1 | 0.215 | |
PAOP, mm Hg | Sepsis | 9 ± 4 | 25 ± 10a | 24 ± 14a | 0.021 |
Sham | 6 ± 1 | 14 ± 8 | 11 ± 7 | 0.313 | |
Urine output, ml/h | Sepsis | 89 ± 48 | 118 ± 80 | 71 ± 40 | 0.147 |
Sham | 116 ± 70 | 175 ± 60 | 150 ± 70 | 0.156 | |
Cumulative amount of fluids, ml | Sepsis | 1,100 ± 390 | 3,180 ± 834 | 4,425 ± 1,160 | - |
Sham | 1,250 ± 350 | 3,370 ± 450 | 4,670 ± 880 | - |