Table 2 Clinical, biological and echocardiographic parameters measured before and during spontaneous breathing trial
| Â | Baseline | Spontaneous breathing trial | ||||
|---|---|---|---|---|---|---|
| Â | Success of weaning n = 48 | Weaning failure n = 20 | P | Success of weaning n = 48 | Weaning failure n = 20 | P |
Mean blood pressure (mmHg) | 132 (122 to 144) | 135 (125 to 135) | 0.91 | 145 (131 to 155) | 175 (149 to 180) | 0.0007 |
Heart rate (beats/min) | 93 (79 to 106) | 98 (82 to 105) | 0.75 | 102 (87 to 110) | 120 (106 to 122) | 0.002 |
Inspiratory pressure support (cm H2O) | 11 (10 to 12) | 12 (10 to 13) | 0.17 | 7 (7 to 7) | 7 (7 to 7) | > 0.99 |
PEP (cm H2O) | 5 (5 to 5) | 5 (5 to 5) | 0.45 | 0 (0 to 0) | 0 (0 to 0) | > 0.99 |
Respiratory rate (breaths/min) | 20 (16 to 25) | 28 (24 to 30) | 0.0008 | 23 (19 to 28) | 45 (39 to 49) | < 0.0001 |
RR/VT | 46 (26 to 58) | 66 (55 to 78) | 0.0005 | 50 (30 to 66) | 136 (130 to 156) | < 0.0001 |
Arterial pH | 7.45 (7.41 to 7.48) | 7.45 (7.42 to 7.5) | 0.46 | 7.45 (7.41 to 7.48) | 7.43 (7.38 to 7.49) | 0.27 |
PAO2/FIO2 | 260 (235 to 303) | 214 (206 to 253) | 0.02 | 227 (211 to 254) | 167 (149 to 200) | 0.0002 |
PCO2 (mmHg) | 37 (33 to 42) | 38 (36 to 43) | 0.29 | 37 (34 to 41) | 43 (37 to 50) | 0.005 |
E wave (cm/sec) | 72 (62 to 91) | 80 (67 to 108) | 0.14 | 80 (69 to 107) | 105 (91 to 125) | 0.007 |
DTE (msec) | 215 (179 to 266) | 170 (160 to 223) | 0.03 | 181 (150 to 205) | 155 (128 to 180) | 0.04 |
Ea (cm/sec) | 8 (7 to 10) | 7 (6 to 8) | 0.01 | 10 (8 to 12) | 7 (6 to 8) | 0.0003 |
E/Ea | 8.9 (7.2 to 11.3) | 13.4 (8.5 to 16.4) | 0.001 | 8.4 (7.1 to 11.6) | 15.7 (13.4 to 21.1) | < 0.0001 |