Skip to main content

Advertisement

Table 1 Characteristics of included studies

From: Brain natriuretic peptide for prediction of mortality in patients with sepsis: a systematic review and meta-analysis

Marker Study Country Setting Population NO. Male (%) Age (year) Outcome Mortality (%)
NT-proBNP Varpula 2007 [28] Finland 24 ICUs Severe sepsis or septic shock 254 69 59 ± 15 In-hospital mortality 26
  Mokart 2007 [29] France ICU Cancer patients developing septic shock 51 63 56 (50 - 68) ICU mortality 51
  Roch 2005 [31] France General ICU Septic shock 39 82.1 63 ± 12 ICU mortality 56
  Brueckmann 2005 [32] Germany Three departments in one hospital Severe sepsis 57 74 55.0 ± 16.3 28-day mortality 28
  Sturgess 2010b* [23] Australia ICU Septic shock 21 61.9 65 ± 17 In-hospital mortality 29
BNP Perman 2011 [22] USA Emergency departments of 10 centers Clinical evidence of sepsis 825 49 53.5 ± 19.6 A composite of events § 6.6
  Zhao 2009 [24] China Surgical ICU Severe sepsis or septic shock 102 53.9 28-day mortality 38.2
  Chen 2009 [25] China Emergency department Sepsis 327 60.6 69.5 ± 13.4 28-day mortality 37.3
  Yucel 2008 [26] Turkey General ICU Sepsis 40 28-day mortality 50
  Post 2008 [27] Germany ICU Septic shock 93 55 65(53 - 73.5) 30-day mortality 40.9
  Ueda 2006 [30] Japan Department of Emergency and Critical Care Medicine Septic shock 22 77.3 62.5 ± 19.3 28-day mortality 54.5
  Charpentier 2004 [33] France Medical ICU Severe sepsis or septic shock 34 47.1 56 ± 15.7 28-day mortality 29
  Sturgess 2010a* [23] Australia ICU Septic shock 21 61.9 65 ± 17 In-hospital mortality 29
  1. BNP = brain natriuretic peptide, NT-proBNP = N-terminal pro-B-type natriuretic peptide, ICU = intensive care unit. *The study reported both BNP (Sturgess 2010a) and NT-proBNP (Sturgess 2010b). Median (25th - 75th percentiles). Dash indicates that information was not provided. §Events include in-hospital mortality, severe sepsis, or septic shock within 30 days following presentation. Anesthesiology Department, Cardiosurgical Anesthesiology Department, and Internal Medicine Department.