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Table 1 The baseline clinical characteristics of the patients

From: Using angiogenic factors and their soluble receptors to predict organ dysfunction in patients with disseminated intravascular coagulation associated with severe trauma

  

DIC

P value

 

Non-DIC

JAAM DIC

ISTH overt DIC

 
 

( n = 27)

( n = 21)

( n = 9)

 

Age (years)

50.0 ± 3.7

43.9 ± 4.5

57.2 ± 7.6

0.273

Gender (male/female)

19/8

10/11

4/5

0.192

ISS

26.0 ± 2.7

27.8 ± 2.3

31.7 ± 4.9

0.394

APACHE II score

19.2 ± 1.3

18.0 ± 1.1

24.4 ± 3.6

0.277

SOFA score max

4.5 ± 0.4

5.9 ± 0.5

9.8 ± 1.3

< 0.001

Sepsis (yes/no)

2/25

1/20

1/8

0.813

P/F ratio min

197 ± 21

185 ± 24

134 ± 35

0.194

ARDS (yes/no)

14/13

11/10

6/3

0.823

JAAM DIC max

2.6 ± 0.3

4.9 ± 0.2

6.6 ± 0.44

< 0.001

ISTH DIC max

2.0 ± 0.1

3.4 ± 0.1

5.4 ± 0.2

< 0.001

Packed red blood cell (ml)

491 ± 144

914 ± 174

2436 ± 594

0.001

Massive transfusion (yes/no)

3/24

5/16

5/4

0.026

FFP (ml)

445 ± 148

1032 ± 429

2503 ± 1011

0.004

Platelet concentrate (U)

3.5 ± 8.9

7.4 ± 3.2

26.7 ± 12.4

0.032

Outcome (survived/died)

26/1

20/1

6/3

0.029

  1. DIC, disseminated intravascular coagulation; ISS, Injury Severity Score; APACHE, Acute Physiology and Chronic Health Evaluation; SOFA, Sequential Organ Failure Assessment; MODS, multiple organ dysfunction syndrome; JAAM, Japan Association for Acute Medicine; ISTH, International Society on Thrombosis and Haemostasis; FFP, fresh frozen plasma. We defined the maximum or minimum score as the highest or lowest score on day1, day3 and day5, when we collected the patient data and samples. Packed red blood cells, FFP, and Platelet concentrate indicate the total volume within 5 days after injury.