From: Correlation between high blood IL-6 level, hyperglycemia, and glucose control in septic patients
 | Overall | Successful glucose control group | Failed glucose control group | P value |
---|---|---|---|---|
n | 153 | 94 | 59 | Â |
Age (years) | 64.6 ± 14.2 | 65.4 ± 15.1 | 63.4 ± 12.6 | 0.394a |
Gender (male) | 109 (71.2%) | 74 (78.7%) | 35 (59.3%) | < 0.01b |
Medical/surgical, medical | 57 (37.2%) | 36 (38.3%) | 21 (35.6%) | 0.736b |
Diabetes mellitus | 41 (26.8%) | 24 (25.5%) | 17 (28.8%) | 0.656b |
On ICU admission | Â | Â | Â | Â |
   APACHE II score | 23.5 ± 7.0 | 22.5 ± 7.1 | 25.2 ± 6.6 | 0.018a |
   SOFA score | 8.2 ± 3.5 | 7.8 ± 3.7 | 8.7 ± 3.1 | 0.109a |
   White blood cells (/mm3) | 14,300 ± 10,300 | 15,100 ± 10,800 | 13,000 ± 9,500 | 0.218a |
   C-reactive protein (mg/dl) | 19.5 ± 10.0 | 18.6 ± 9.8 | 20.8 ± 10.3 | 0.203a |
   Lactate (mg/dl) | 3.8 ± 2.8 | 3.4 ± 2.8 | 4.4 ± 2.8 | 0.035a |
   IL-6 (pg/ml) | 13,800 ± 48,800 | 5,350 ± 13,800 | 27,200 ± 75,100 | < 0.0001a |
Type of sepsis | Â | Â | Â | < 0.001b |
   Sepsis | 30 (19.6%) | 27 (28.7%) | 3 (5.1%) |  |
   Severe sepsis | 86 (56.2%) | 56 (59.6%) | 30 (50.8%) |  |
   Septic shock | 37 (24.2%) | 11 (11.7%) | 26 (44.1%) |  |
Primary source of infection | Â | Â | Â | 0.276b |
   Central nervous system | 5 (3.3%) | 2 (2.1%) | 3 (5.1%) |  |
   Neck/mediastinum | 19 (12.4%) | 11 (11.7%) | 8 (13.6%) |  |
   Lung | 45 (29.4%) | 33 (35.1%) | 12 (20.2%) |  |
   Abdomen | 47 (30.7%) | 25 (26.6%) | 22 (37.3%) |  |
   Urinary tract | 16 (10.5%) | 8 (8.5%) | 8 (13.6%) |  |
   Bones/joints/soft tissue | 12 (7.8%) | 7 (7.4%) | 5 (8.5%) |  |
   Others | 9 (5.9%) | 8 (8.5%) | 1 (1.7%) |  |
Implementation of enteral nutrition within 7 days | 89 (58.2%) | 55 (58.5%) | 34 (58.2%) | 0.914b |
Start of enteral nutrition after ICU admission (days) | 3.5 ± 2.1 | 3.7 ± 2.1 | 3.3 ± 2.1 | 0.446 |