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Table 1 Patients' background factors

From: Correlation between high blood IL-6 level, hyperglycemia, and glucose control in septic patients

 

Overall

Successful glucose control group

Failed glucose control group

P value

n

153

94

59

 

Age (years)

64.6 ± 14.2

65.4 ± 15.1

63.4 ± 12.6

0.394a

Gender (male)

109 (71.2%)

74 (78.7%)

35 (59.3%)

< 0.01b

Medical/surgical, medical

57 (37.2%)

36 (38.3%)

21 (35.6%)

0.736b

Diabetes mellitus

41 (26.8%)

24 (25.5%)

17 (28.8%)

0.656b

On ICU admission

    

   APACHE II score

23.5 ± 7.0

22.5 ± 7.1

25.2 ± 6.6

0.018a

   SOFA score

8.2 ± 3.5

7.8 ± 3.7

8.7 ± 3.1

0.109a

   White blood cells (/mm3)

14,300 ± 10,300

15,100 ± 10,800

13,000 ± 9,500

0.218a

   C-reactive protein (mg/dl)

19.5 ± 10.0

18.6 ± 9.8

20.8 ± 10.3

0.203a

   Lactate (mg/dl)

3.8 ± 2.8

3.4 ± 2.8

4.4 ± 2.8

0.035a

   IL-6 (pg/ml)

13,800 ± 48,800

5,350 ± 13,800

27,200 ± 75,100

< 0.0001a

Type of sepsis

   

< 0.001b

   Sepsis

30 (19.6%)

27 (28.7%)

3 (5.1%)

 

   Severe sepsis

86 (56.2%)

56 (59.6%)

30 (50.8%)

 

   Septic shock

37 (24.2%)

11 (11.7%)

26 (44.1%)

 

Primary source of infection

   

0.276b

   Central nervous system

5 (3.3%)

2 (2.1%)

3 (5.1%)

 

   Neck/mediastinum

19 (12.4%)

11 (11.7%)

8 (13.6%)

 

   Lung

45 (29.4%)

33 (35.1%)

12 (20.2%)

 

   Abdomen

47 (30.7%)

25 (26.6%)

22 (37.3%)

 

   Urinary tract

16 (10.5%)

8 (8.5%)

8 (13.6%)

 

   Bones/joints/soft tissue

12 (7.8%)

7 (7.4%)

5 (8.5%)

 

   Others

9 (5.9%)

8 (8.5%)

1 (1.7%)

 

Implementation of enteral nutrition within 7 days

89 (58.2%)

55 (58.5%)

34 (58.2%)

0.914b

Start of enteral nutrition after ICU admission (days)

3.5 ± 2.1

3.7 ± 2.1

3.3 ± 2.1

0.446

  1. Data presented as mean ± standard deviation or n (%). See 'Patient management for glucose control' in Materials and methods for definition of successful glucose control. APACHE, Acute Physiology and Chronic Health Evaluation; SOFA: Sequential Organ Failure Assessment. aUnpaired t test. bChi-square test.