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Table 2 Clinical outcomes

From: Moderate glucose control results in less negative nitrogen balances in medical intensive care unit patients: a randomized, controlled study

Outcome variable

MIT group (n= 55)

CIT group (n= 57)

P value

Mean blood glucose (mg/dl)

125.3 ± 17.8

199.9 ± 30.2

< 0.01

Daily dose of insulin (unit/day)

82 (69 to 111)

37 (26 to 44)

< 0.01

ICU days

14 (9 to 19)

15 (11 to 26)

0.26

Ventilator days

20 (11 to 30)

23 (11 to 43.5)

0.19

Hospital days

27 (15 to 36)

32 (18.5 to 51.3)

0.052

Acute renal injury

3/55 (5.5%)

7/57 (12.3%)

0.10

Bloodstream infection

1/55 (1.8%)

3/57 (5.3%)

0.33

Red-blood-cell blood transfusion

12/55 (21.8%)

15/57 (26.3%)

0.74

Gastrointestinal bleeding

7/55 (12.7%)

7/57 (12.3%)

0.83

Number of mild hypoglycemia

10/55 (18.2%)

6/57 (10.5%)

0.37

Rate of moderate hypoglycemia per 100 treatment days

2.4

1.5

0.18

Number of severe hypoglycemia

2/55 (3.6%)

1/57 (1.8%)

0.53

Rate of severe hypoglycemia per 100 treatment days

0.3

0.2

0.44

Hospital mortality rate

18/55 (32.7%)

28/57 (49.1%)

0.08

  1. Data presented as n, mean ± standard deviation, or median (interquartile range). CIT, conventional insulin therapy; MIT, moderate insulin therapy.