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Table 2 Studies applying hypothermia to patients with symptomatic vasospasm refractory to conventional treatment

From: Hypothermia after aneurysmal subarachnoid hemorrhage

Study Number of patients (n) Target temperature (°C) Duration of hypothermia (days) Favorable outcome*, % (n) Mortality rate, % (n)
Nagao and colleagues (2000) 5 32 to 34 5 to 14 80.0% (4) 0.0% (0)
Nakamura and colleagues (2002) 5 32 to 34 5 to 14 40.0% (2) 60.0% (3)
Nagao and colleagues (2003) 8 32 to 34 5 to 12 87.5% (7) 0.0% (0)
Seule and colleagues (2009) 28 33 to 34 1 to 16 57.1% (16) 28.6% (8)
Total 46    63.0% (29) 26.1% (12)
  1. Note: *GOS ≥4 or mRS ≤3.