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Table 2 Studies applying hypothermia to patients with symptomatic vasospasm refractory to conventional treatment

From: Hypothermia after aneurysmal subarachnoid hemorrhage

Study

Number of patients (n)

Target temperature (°C)

Duration of hypothermia (days)

Favorable outcome*, % (n)

Mortality rate, % (n)

Nagao and colleagues (2000)

5

32 to 34

5 to 14

80.0% (4)

0.0% (0)

Nakamura and colleagues (2002)

5

32 to 34

5 to 14

40.0% (2)

60.0% (3)

Nagao and colleagues (2003)

8

32 to 34

5 to 12

87.5% (7)

0.0% (0)

Seule and colleagues (2009)

28

33 to 34

1 to 16

57.1% (16)

28.6% (8)

Total

46

  

63.0% (29)

26.1% (12)

  1. Note: *GOS ≥4 or mRS ≤3.