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Table 2 Diagnostic findings of patients with hyperferritinemia and secondary HLH/sepsis/MODS/MAS

From: Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment?

Variable Secondary HLH/MAS (n= 23), percentage (number)
Fever 100 (23)
Splenomegaly 65 (15)
Cytopenia 96 (22)
Anemia 96 (22)
Thrombocytopenia 91 (21)
Neutropenia 44 (10)
Hypertriglyceridemia 87 (20)
Hypofibrinogenemia 39 (9)
Hyperferritinemia 100 (23)
Hemophagocytosis in bone marrow 100 (23)
Survival 87 (20)
  1. All of the patients met five or more of the criteria required for a diagnosis of hemophagocytic lymphohistiocytosis/macrophage activation syndrome (HLH/MAS). HLH, hemophagocytic lymphohistiocytosis; MAS, macrophage activation syndrome; MODS, multiple organ dysfunction syndrome.