Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment?

Table 1 Baseline characteristics of patients with hyperferritinemia and secondary HLH/sepsis/MODS/MAS

Variable	Patients with secondary HLH/MAS (n= 23)
	Mean ± SD	Median	Range
Age, years	7.2 ± 3.6	6.7	2-15
PRISM III-24 score	23.9 ± 12.5	19.5	7-48
PELOD score	26 ± 13.8	24	4-53
Number of dysfunctional organs	4.6 ± 1	5	3-6
	Percentage	Number
Males/Females	74/26	17/6
Artificial ventilation	87	20
Underlying disease	78	18

HLH, hemophagocytic lymphohistiocytosis; MAS, macrophage activation syndrome; MODS, multiple organ dysfunction syndrome; PELOD, Pediatric Logistic Organ Dysfunction; PRISM, Pediatric Risk of Mortality; SD, standard deviation.

ISSN: 1364-8535