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Figure 5 | Critical Care

Figure 5

From: Cannabinoid receptor 2 activation reduces intestinal leukocyte recruitment and systemic inflammatory mediator release in acute experimental sepsis

Figure 5

Colon ascendens stent peritonitis-induced sepsis - inflammatory mediators (pg/ml). (A) TNFα, (B) IL-1β, (C) intercellular adhesion molecule (ICAM), (D) vascular cell adhesion molecule (VCAM), (E) RANTES, and (F) macrophage inflammatory protein-2 (MIP-2): SHAM, control group (n = 9); colon ascendens stent peritonitis (CASP), sepsis group (n = 9); CASP + HU308 (2.5/10 mg/kg), CASP plus cannabinoid receptor 2 agonist (2.5 or 10 mg/kg HU308; n = 9). Data presented as mean ± standard deviation. *P <0.05 versus SHAM. #P <0.05 versus CASP.

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Critical Care

ISSN: 1364-8535