Table 2 Methodological features and results of recent clinical trials comparing advanced life support treatment with or without drugs
From: Is there still a place for vasopressors in the treatment of cardiac arrest?
Author, year [ref] | Study design | Actual/planned sample size (%) | Treatment in the intervention group | Treatment in the control group | Controlled for CPR quality | Causes of death documented | Survival (%) | |
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Â | Â | Â | ROSC | Discharge |
Olasveengen, 2009 [34] | Randomized, open-label | 851/900 (94.6%) | Epinephrine, amiodarone, atropine | No drug or venous access up to 5 minutes after ROSC | Yes | Yes | 26.1 | 9.9 |
Jacobs, 2011 [35] | Randomized, double-blind placebo-controlled | 534/4426 (12.1%) | Epinephrine | Intravenous placebo | No | No | 16.1 | 3.0 |