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Table 1 Summary of the characteristics of the clinical trials that have compared vasopressin with epinephrine in cardiac arrest

From: Is there still a place for vasopressors in the treatment of cardiac arrest?

Author, year [ref] Setting Number of enrolled patients Intervention Mean time to first vasopressin bolus, min
Lindner, 1997 [26] OHCA 40 Vasopressin 40 IU followed by epinephrine 13.9
Stiell, 2001 [27] IHCA 200 Vasopressin 40 IU followed by epinephrine 6.7
Wenzel, 2004 [29] OHCA 1186 Vasopressin 40 IU for up to 2 cycles, followed by epinephrine 17.5
Gueugniaud, 2008 [30] OHCA 2894 Vasopressin 40 IU plus epinephrine for up to 2 cycles, followed by epinephrine 21.4
Mentzelopoulos, 2009 [31] IHCA 100 Vasopressin 20 IU plus epinephrine for up to 5 cycles, plus methylprednisolone 40 mg (once only) < 5
  1. Treatment in the control group was epinephrine in all studies. IHCA, in-hospital cardiac arrest; IU, International Units; OHCA, out of-hospital cardiac arrest.