| |
Cause of lung injury
|
Demographics
|
Respiratory variables
| | |
|---|
|
Patient
|
Disorders predisposing to ARDS
|
Underlying disease
|
SAPS II
|
Body mass index
|
PaO2/FiO2 ratio
|
Plateau pressure (cmH2O)
|
PEEP (cmH2O)
|
FiO2
|
PaCO2 (mmHg)
|
pH
|
Days on ventilator
|
Outcomes
|
|---|
|
1
|
Aspiration
|
Brain injury
|
34
|
29.3
|
152
|
26
|
9
|
0.4
|
41
|
7.39
|
16
|
Deceased
|
|
2
|
Severe pulmonary thromboembolism and thrombectomy
|
Parkinson's disease
|
33
|
25.7
|
190
|
32
|
10
|
0.4
|
46
|
7.40
|
3
|
Survived
|
|
3
|
Sepsis, liver failure after valproate administration
|
Endometritis, epilepsy
|
35
|
31.1
|
153
|
30
|
14
|
0.5
|
45
|
7.43
|
5
|
Survived
|
|
4
|
Aspiration
|
Subarachnoid haemorrhage
|
33
|
27.6
|
190
|
28
|
9
|
0.5
|
44
|
7.48
|
3
|
Deceased
|
|
5
|
Aspiration
|
Gastric ulcer perforation
|
34
|
29.9
|
153
|
36
|
13
|
0.6
|
49
|
7.32
|
2
|
Survived
|
|
6
|
Sepsis, aspiration
|
Colon diverticulitis
|
42
|
30.4
|
118
|
46
|
22
|
0.8
|
65
|
7.30
|
47
|
Deceased
|
|
Mean ± SD
| | |
35 ± 3
|
29 ± 2
|
159 ± 27
|
33 ± 7
|
13 ± 5
|
0.5 ± 02
|
48 ± 9
|
7.39 ± 0.07
|
18 ± 11
| |
- aPatient 2 developed ARDS after embolectomy and three days of mechanical ventilation at pulmonary artery wedge pressures below 18 mmHg. Patient 6 developed ARDS already at admission due to a combination of sepsis after bowel suture insufficiency and aspiration and was treated with lung-protective ventilation already for 47 days at study entry. ARDS, acute respiratory distress syndrome; FiO2, fraction of inspired oxygen pressure; PaCO2, arterial carbon dioxide pressure; PaO2/FiO2, arterial oxygen-to-fraction of inspired oxygen pressure ratio; PEEP, positive end-expiratory pressure; SAPS II, Simplified Acute Physiology Score II [15].
