Skip to main content

Table 1 Clinical characteristics and respiratory variables of the patients within 12 hours before study entrya

From: Negative- versus positive-pressure ventilation in intubated patients with acute respiratory distress syndrome

 

Cause of lung injury

Demographics

Respiratory variables

  

Patient

Disorders predisposing to ARDS

Underlying disease

SAPS II

Body mass index

PaO2/FiO2 ratio

Plateau pressure (cmH2O)

PEEP (cmH2O)

FiO2

PaCO2 (mmHg)

pH

Days on ventilator

Outcomes

1

Aspiration

Brain injury

34

29.3

152

26

9

0.4

41

7.39

16

Deceased

2

Severe pulmonary thromboembolism and thrombectomy

Parkinson's disease

33

25.7

190

32

10

0.4

46

7.40

3

Survived

3

Sepsis, liver failure after valproate administration

Endometritis, epilepsy

35

31.1

153

30

14

0.5

45

7.43

5

Survived

4

Aspiration

Subarachnoid haemorrhage

33

27.6

190

28

9

0.5

44

7.48

3

Deceased

5

Aspiration

Gastric ulcer perforation

34

29.9

153

36

13

0.6

49

7.32

2

Survived

6

Sepsis, aspiration

Colon diverticulitis

42

30.4

118

46

22

0.8

65

7.30

47

Deceased

Mean ± SD

  

35 ± 3

29 ± 2

159 ± 27

33 ± 7

13 ± 5

0.5 ± 02

48 ± 9

7.39 ± 0.07

18 ± 11

 
  1. aPatient 2 developed ARDS after embolectomy and three days of mechanical ventilation at pulmonary artery wedge pressures below 18 mmHg. Patient 6 developed ARDS already at admission due to a combination of sepsis after bowel suture insufficiency and aspiration and was treated with lung-protective ventilation already for 47 days at study entry. ARDS, acute respiratory distress syndrome; FiO2, fraction of inspired oxygen pressure; PaCO2, arterial carbon dioxide pressure; PaO2/FiO2, arterial oxygen-to-fraction of inspired oxygen pressure ratio; PEEP, positive end-expiratory pressure; SAPS II, Simplified Acute Physiology Score II [15].