|
Parameter
|
Statistics
|
Placebo
|
Inhaled NO
|
P Value
|
|---|
|
FEV1, L
|
N
|
41
|
51
| |
| |
Mean ± SD
|
2.29 ± 0.71
|
2.64 ± 0.91
|
0.1161
|
|
FEV1, % predicted
|
N
|
41
|
50
| |
| |
Mean ± SD
|
69.51 ± 28.97
|
80.23 ± 21.21
|
0.042
|
|
FEV1/FVC, %
|
N
|
40
|
51
| |
| |
Mean ± SD
|
72.89 ± 20.20
|
77.45 ± 15.19
|
0.155
|
|
FEV1/FVC, % predicted
|
N
|
37
|
49
| |
| |
Mean ± SD
|
87.92 ± 19.77
|
96.14 ± 13.79
|
0.033
|
|
FVC, L
|
N
|
41
|
51
| |
| |
Mean ± SD
|
3.01 ± 0.96
|
3.36 ± 1.09
|
0.163
|
|
FVC, % predicted
|
N
|
41
|
50
| |
| |
Mean ± SD
|
69.84 ± 27.40
|
83.78 ± 19.38
|
0.019
|
|
FEF25-75%, L/sec
|
N
|
41
|
51
| |
| |
Mean ± SD
|
12.25 ± 55.86
|
26.34 ± 84.50
|
0.121
|
|
FEF25-75%, % predicted
|
N
|
41
|
50
| |
| |
Mean ± SD
|
62.96 ± 36.26
|
72.50 ± 27.71
|
0.154
|
|
FRC, L
|
N
|
33
|
44
| |
| |
Mean ± SD
|
2.64 ± 0.71
|
3.00 ± 0.94
|
0.113
|
|
FRC, % predicted
|
N
|
32
|
43
| |
| |
Mean ± SD
|
78.19 ± 29.95
|
93.98 ± 25.55
|
0.109
|
|
TLC, L
|
N
|
32
|
44
| |
| |
Mean ± SD
|
4.81 ± 1.00
|
5.54 ± 1.42
|
0.026
|
|
TLC, % predicted
|
N
|
31
|
43
| |
| |
Mean ± SD
|
76.10 ± 21.84
|
93.33 ± 18.21
|
< 0.001
|
|
CO diffusion, mL/min/mm Hg
|
N
|
33
|
42
| |
| |
Mean ± SD
|
17.87 ± 6.37
|
18.25 ± 6.77
|
0.709
|
|
CO diffusion, % predicted
|
N
|
32
|
42
| |
| |
Mean ± SD
|
65.96 ± 23.23
|
71.02 ± 20.79
|
0.492
|
- FEF, forced expiratory flow; FEV1, forced expiratory volume in 1 second; FRC, functional residual capacity; FVC, forced vital capacity; N, number; NO, nitric oxide; TLC, total lung capacity.
