Association between inhaled nitric oxide treatment and long-term pulmonary function in survivors of acute respiratory distress syndrome

Table 4 Pulmonary function test results at six months

Parameter	Statistics	Placebo	Inhaled NO	P Value
FEV₁, L	N	41	51
	Mean ± SD	2.29 ± 0.71	2.64 ± 0.91	0.1161
FEV₁, % predicted	N	41	50
	Mean ± SD	69.51 ± 28.97	80.23 ± 21.21	0.042
FEV₁/FVC, %	N	40	51
	Mean ± SD	72.89 ± 20.20	77.45 ± 15.19	0.155
FEV₁/FVC, % predicted	N	37	49
	Mean ± SD	87.92 ± 19.77	96.14 ± 13.79	0.033
FVC, L	N	41	51
	Mean ± SD	3.01 ± 0.96	3.36 ± 1.09	0.163
FVC, % predicted	N	41	50
	Mean ± SD	69.84 ± 27.40	83.78 ± 19.38	0.019
FEF_25-75%, L/sec	N	41	51
	Mean ± SD	12.25 ± 55.86	26.34 ± 84.50	0.121
FEF_25-75%, % predicted	N	41	50
	Mean ± SD	62.96 ± 36.26	72.50 ± 27.71	0.154
FRC, L	N	33	44
	Mean ± SD	2.64 ± 0.71	3.00 ± 0.94	0.113
FRC, % predicted	N	32	43
	Mean ± SD	78.19 ± 29.95	93.98 ± 25.55	0.109
TLC, L	N	32	44
	Mean ± SD	4.81 ± 1.00	5.54 ± 1.42	0.026
TLC, % predicted	N	31	43
	Mean ± SD	76.10 ± 21.84	93.33 ± 18.21	< 0.001
CO diffusion, mL/min/mm Hg	N	33	42
	Mean ± SD	17.87 ± 6.37	18.25 ± 6.77	0.709
CO diffusion, % predicted	N	32	42
	Mean ± SD	65.96 ± 23.23	71.02 ± 20.79	0.492

FEF, forced expiratory flow; FEV₁, forced expiratory volume in 1 second; FRC, functional residual capacity; FVC, forced vital capacity; N, number; NO, nitric oxide; TLC, total lung capacity.

ISSN: 1364-8535