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Table 1 Hemodynamic variables

From: Effects of pulmonary acid aspiration on the lungs and extra-pulmonary organs: a randomized study in pigs

 

T0

T60

T120

T240

HR, min -1

    

Control

79.0 ± 23.0

86.0 ± 16.0

96.0 ± 19.0

85.0 ± 20.0

AAP

90.5 ± 19..2

80.7 ± 21.2

69.7 ± 12.9

71.9 ± 9.0

MAP, mmHg

    

Control

76.0 ± 15.0

81.0 ± 21.0

80.0 ± 14.0

74.0 ± 12.0

AAP

83.9 ± 24.7

73.4 ± 8.0

69.9 ± 5.7

86.5 ± 16.9

CVP, mmHG

    

Control

6.7 ± 4.0

6.7 ± 4.5

6.2 ± 4.3

7.2 ± 3.7

AAP

8.2 ± 3.3

11.5 ± 3.3

12.5 ± 1.5°

13.6 ± 3.9°

mPAP, mmHG

    

Control

23.3 ± 4.7

21.1 ± 2.4

21.2 ± 2.1

21.0 ± 4.2

AAP

21.3 ± 6.0

31.4 ± 9.8*°

32.3 ± 8.3*°

30.3 ± 3.1*°

CO, l.min -1

    

Control

7.5 ± 1.5

7.1 ± 1.6

7.3 ± 1.3

6.9 ± 1.0

AAP

8.1 ± 2.4

7.1 ± 2.1

7.4 ± 1.4

6.7 ± 1.2

SV, ml

    

Control

82.0 ± 18.0

80.0 ± 22.0

78.0 ± 17.0

81.0 ± 20.0

AAP

94.6 ± 17.1

104 ± 29.1

104 ± 28.1

103 ± 37.9

SVV, %

    

Control

9.7 ± 3.2

10.1 ± 3.6

9.1 ± 2.3

7.6 ± 2.4

AAP

9,9 ± 7.3

9.7 ± 4.8

9.2 ± 4.5

9.8 ± 3.2

ITBI, ml.m 2

    

Control

729 ± 125

704 ± 91.0

711 ± 83.0

755 ± 98.0

AAP

793 ± 103

842 ± 172

896 ± 171

902 ± 162

ELWI, ml/kg

    

Control

9.0 ± 1.9

8.6 ± 1.4

8.5 ± 1.5

8.9 ± 1.1

AAP

8.2 ± 1.9

9.9 ± 1.9

12.5 ± 4.3*

14.5 ± 5.2*°

GEF, %

    

Control

38.1 ± 7.2

37.5 ± 8.4

37.2 ± 7.6

36.9 ± 8.5

AAP

37.4 ± 2.6

40.7 ± 5.4

37.3 ± 4,.2

39.1 ± 5.4

RVEF, %

    

Control

36.6 ± 7.1

39.7 ± 15.1

39.1 ± 8.5

35.7 ± 7.6

AAP

41.1 ± 2.1

31.0 ± 7.6*

32.2 ± 5.5*

29.7 ± 6.7*

RVEDV, ml

    

Control

199 ± 54

194 ± 55

198 ± 49

202 ± 63.0

AAP

210 ± 40

232 ± 71

245 ± 83

293 ± 136

RHEDV, ml

    

Control

387 ± 110

389 ± 108

400 ± 101

421 ± 114

AAP

415 ± 62.4

437 ± 108

459 ± 96

535 ± 213

LHEDV, ml

    

Control

557 ± 174

515 ± 122

511 ± 138

550 ± 112

AAP

559 ± 139

581 ± 149

640 ± 209

566 ± 185

  1. Values are the mean (SD) of seven. AAP, acid aspiration pneumonitis; CO, cardiac output; Control, control animals; CVP, central venous pressure; ELWI, extravascular lung water index; GEF, global ejection fraction; HR, heart rate; ITBI, intrathoracic blood volume index; LHEDV, left heart end-diastolic volume; MAP, mean arterial pressure; mPAP, mean pulmonary artery pressure; RHEDV, right heart end-diastolic volume; RVEDV, right ventricular end-diastolic volume; RVEF, right ventricular ejection fraction; SRVEF, right ventricular ejection fraction; SVV, stroke volume variation; V, stroke volume. * P < 0.05 vs. T0;°P < 0.05 Control vs. AAP