Skip to main content

Table 1 Metabolites from plasma samples of healthy and polymicrobial infected mice

From: Arginine metabolism is markedly impaired in polymicrobial infected mice

Metabolite Healthy controls 6 hours post sepsis 24 hours post sepsis
Arginine (μM) 101.97 ± 8.12 78.25 ± 5.10 43.65 ± 10.06 †‡
Proline (μM) 65.00 ± 4.98 34.79 ± 3.89 29.99 ± 5.18
Ornithine (μM) 55.84 ± 3.41 30.04 ± 3.63 28.31 ± 4.64
Putrescine (μM) 0.40 ± 0.03 0.19 ± 0.06 4.51 ± 1.81*
Urea (mg/dl) 28.08 ± 1.57 36.42 ± 2.09 55.61 ± 7.05*
Glutamine (μM) 590.40 ± 118.91 635.30 ± 107.15 548.50 ± 105.21
Citrulline (μM) 47.67 ± 3.56 45.79 ± 7.18 50.16 ± 4.96
Acetylornithine (μM) 2.48 ± 0.15 2.65 ± 0.33 2.08 ± 0.12
Glutamic acid (μM) 18.68 ± 3.33 14.04 ± 4.30 34.38 ± 11.64
Spermidine (μM) 0.49 ± 0.02 0.43 ± 0.06 0.08 ± 0.05 †‡
  1. Data presented as mean ± standard error of the mean. Investigated metabolites from plasma samples of healthy controls (n = 10) and of polymicrobial infected mice 6 hours (n = 10) and 24 hours (n = 10) post sepsis induction. Statistical analysis by one-way analysis of variance (ANOVA) and post-hoc tests using the Scheffé procedure. *Statistically significant difference compared with healthy controls (P ≤ 0.05; ANOVA). Statistically significant difference compared with healthy controls (P ≤ 0.001; ANOVA). Statistically significant difference between 6 hours and 24 hours post sepsis induction (P ≤ 0.05; ANOVA). Significant data are indicated in bold.