| Â | PRBC | PLT |
|---|
| Â | "fresh PRBC" | "stored PRBC" | "fresh PLT" | "stored PLT" |
|---|
Hb (g/dL) | 0.01 | 0.33 | 0.01 | 0.02 |
K+ (mmol/L) | 2.0 | 44.4 | 3.9 | 4.4 |
Na+ (mmol/L) | 143 | 105 | 157 | 158 |
Cl- (mmol/L) | 112 | 103 | 74 | 77 |
Glucose (mmol/L) | 28.0 | 14.3 | 7.0 | 0.0 |
Lactate (mmol/L) | 6.5 | 29.6 | 4.6 | 18.0 |
sCD40L (ng/ml) | 0.24 | 1.50 | 0.48 | 0.73 |
EGF (pg/ml) | 0 | 298 | 5 | 69 |
ENA-78 (pg/ml) | 63 | 1,555 | 226 | 6,333 |
GRO-α (pg/ml) | 352 | 662 | 110.1 | 692 |
IL-8 (pg/ml) | 28 | 10,004 | 323 | 379 |
IL-16 (pg/ml) | 50 | 19,754 | 225 | 260 |
MCP-1 (pg/ml) | 0 | 422 | 0 | 0 |
- Cl-, chlorine anion; EGF, epidermal growth factor; ENA-78, epithelial derived neutrophil activating 78; "fresh PLT", pooled heat-inactivated supernatant from Day 1 non-leucoreduced human platelet concentrates; "fresh PRBC", pooled heat-inactivated supernatant from Day 1 non-leucoreduced human packed red blood cell concentrates; GRO-α, growth related oncogene alpha; Hb, haemoglobin; IL-8, interleukin 8; IL-16, interleukin 16; K+, potassium cation; MCP-1, monocyte chemotactic protein 1; Na+, sodium anion; PLT; platelet concentrates; PRBC; packed red blood cell concentrates; sCD40L, soluble CD40 ligand; "stored PLT", pooled heat-inactivated supernatant from Day 5 non-leucoreduced human platelet concentrates; "stored PRBC", pooled heat-inactivated supernatant from Day 42 non-leucoreduced human packed red blood cell concentrates. Both "stored PRBC" and "stored PLT" demonstrated increased levels of lactate and sCD40L as well as decreased pH and glucose levels compared to fresh equivalents. Additionally "stored PRBC" demonstrated increased haemoglobin and potassium levels compared to "fresh PRBC" and to "stored PLT". Higher concentrations of EGF, ENA-78 and GRO-α, were present in both "stored PLT" and "stored PRBC" relative to fresh equivalents. However the concentrations of IL-8, IL-16 and MCP-1 were only increased only "stored PRBC". Additionally, concentrations of EGF, IL-8, IL-16 and MCP-1 were all higher in "stored PRBC" than in "stored PLT". Conversely, concentrations of ENA-78 and GRO-α were higher in "stored PLT" than in "stored PRBC".
